A REVIEW ON EMERGING PATHOGENESIS OF COVID-19 AND POINTS OF CONCERN FOR RESEARCH COMMUNITIES IN NIGERIA.

Background: COVID-19 remains an emerging pandemic that continuously poses an alarming threat and challenge to economic, social and well-being of the people throughout the world. It also remains an evolving disease which complete pathogenesis that translates into clinical features is only just emerging by each second of the day. There have been observations about the emerging trends of the disease in Nigeria like in any other country in the world where there is outbreak.

Cognitive Dysfunction Among Primi gravidae Attending an Ante Natal Clinic in Kano, Northwest Nigeria.

Cognitive deficits among pregnant women have been reported, though the evidence is equivocal. Cognitive dysfunction during pregnancy may have negative consequences on maternal and child health.  Yet, very little is known about cognitive function of pregnant women in general and primi gravidae in particular in the area under study.

Insulin-induced oxidative stress in the brain is nitric oxide-dependent.

Insulin is known to increase brain nitric oxide (NO) level and to cause oxidative stress but the relationship between these phenomena has not been well elucidated. This study aimed to examine the role of NO in the insulin-NO-oxidative stress axis in the brain. Mice were grouped into four (n = 5) and treated for seven days with 0.

Peripheral brain-derived neurotrophic factor is reduced in stroke survivors with cognitive impairment.

Stroke presents a huge burden both globally and locally. Very few studies have evaluated cognitive impairment following stroke in Africa. This study evaluated cognitive impairment in stroke survivors and examined its relationship with peripheral blood levels of brain-derived neurotrophic factor (BDNF).