Colorectal carcinoma under microscopy: patohistology or much more?

Today the role of pathologists is increasingly focused on finding more accurate prognostic and predictive parameters that will be necessary for targeted treatment of patients. Improving understanding of colorectal carcinogenesis allow us to consider incorporation of these new knowledges in molecular classification of colorectal cancer. There are different ways of molecular classification, but most of them are based on: 1.

[Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions].

Background/aim: Fine needle aspiration cytology (FNAC) of the thyroid gland has been used as an initial investigative procedure of thyroid nodule(s) in the Department of Pathology at the Institute of Oncology of Vojvodina for more than 20 years. This procedure is rapid, inexpensive and technologically simple, yet it has found only limited, albeit increasing acceptance in medical practice in Serbia. The aim of the study was to evaluate our FNAC findings by correlating cytological results with histological diagnosis and to define the sensitivity, diagnostic accuracy and positive predictive value of FNAC.

Chronic necrotizing pulmonary aspergillosis.

Introduction: Chronic necrotizing pulmonary aspergillosis (CNPA) is a cavitary, infectious process of lung parenchyma with slow progressive course. Vascular invasion and dissemination to other organs are unusual.

Case Report: We presented a 25-year old man with bilineal acute leukaemia who developed pulmonary and systemic symptoms.

[Cavernous hemangioma of the lung].

Introduction: Cavernous hemangiomas are benign vascular tumours rarely described in the lungs. Symptoms include respiratory distress, cardiac failure and massive haemoptysis, but they are mostly asymptomatic.

Case Report: A 67-year-old woman was referred to our institute and treated for pneumonia.

Pulmonary capillariasis miming bronchial carcinoma.

Pulmonary capillariasis is a zoonotic disease caused by the cosmopolitan nematode Capillaria aerophila, which circulates among wild carnivorous and omnivorous mammals. Only 11 cases have been documented to date. We describe a cryptic case of pulmonary capillariasis in a Serbian woman that resembled a bronchial carcinoma.

Leptomeningeal metastasis from malignant pleural mesothelioma.

Leptomeningeal metastasis from malignant mesothelioma is very rare; to our knowledge, only one imaging report exists in the literature. We present the case of widespread leptomeningeal lesions secondary to a malignant mesothelioma in a 61-year-old woman.

[Pulmonary thromboembolism and acute renal insufficiency caused by renal artery thrombosis].

Introduction: Pulmonary thromboembolism is a clinical and pathophysiological condition caused by occlusion of pulmonary arteries by thrombotic embolus. Deep venous thrombosis needn't necessarily be evident. Acute renal insufficiency is a syndrome manifested by rapid decrease or even complete urinary retention, which may be due to obturation of renal arteries by a thrombus.