Digestibility in the gastrointestinal tract and migration to blood of β'-component (Onk k 5), a major salmon roe IgE-binding protein.

The major allergen of chum salmon (Oncorhynchus keta) roe is the β'-component (Onc k 5, β'-c), which is a yolk protein and a fragment of vitellogenin. When yolk content containing β'-c was orally administered to mice, β'-c passed through the gastrointestinal tract and was excreted in feces without marked degradation. The direct administration of β'-c to ligated jejunal and ileal loops showed that β'-c was absorbed through the small intestine and transferred into the blood.