Microscopic Evaluation of Ovarian Surface Epithelium Following Treatment with Conjugated Estrogens in a Mouse Model.

Background: This study was designed to evaluate the effect of different concentrations of conjugated equine estrogens (CEE) on the ovarian epithelium of female CD1 mice.

Methods: Twenty-four female mice at 7 months with irregular estrus cycles were randomly divided into four groups of 6 mice each. Group one was considered as a control group and received a daily dose of 0.

Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons.

In healthy or pathological brains, the neuroinflammatory state is supported by a strong communication involving microglia and neurons. Recent studies indicate that extracellular vesicles (EVs), including exosomes and microvesicles, play a key role in the physiological interactions between cells allowing central nervous system (CNS) development and/or integrity. The present report used medicinal leech CNS to investigate microglia/neuron crosstalk from ex vivo approaches as well as primary cultures.

The reproductive cycle of the male house gecko, Hemidactylus flaviviridis, in relation to plasma steroid concentrations, progesterone receptors, and steroidogenic ultrastructural features, in Oman.

The annual testicular cycle of the house gecko Hemidactylus flaviviridis in Oman was studied. Plasma testosterone (T), estradiol (E2) and progesterone (P) concentrations were measured using a sensitive HPLC-MS/MS detection technique. The ultrastructural steroidogenic features in Sertoli and Leydig cells, which were the major source of steriodogenesis, were examined, using transmission electron microscopy (TEM).

Antibiofilm activity of Dendrophthoe falcata against different bacterial pathogens.

Dendrophthoe falcata is a hemiparasitic plant commonly used for ailments such as ulcers, asthma, impotence, paralysis, skin diseases, menstrual troubles, pulmonary tuberculosis, and wounds. In this context, the validations of the traditional claim that the leaf extract of D. falcata possesses antibiofilm and anti-quorum sensing activity against different bacterial pathogens were assessed.

Porosity and the effect of structural changes on the mechanical glass transition temperature.

Continuing an investigation on the fundamentals and applications of a recently proposed concept, i.e., the mechanical or network glass transition temperature, we now report data on the macrostructural changes in dehydrated apple tissue in relation to apparent porosity.

Cardiovascular and lung inflammatory effects induced by systemically administered diesel exhaust particles in rats.

Pollution by particulates has consistently been associated with increased cardiorespiratory morbidity and mortality. It has been suggested that ultrafine particles, of which diesel exhaust particles (DEP) are significant contributors, are able to translocate from the airways into the bloodstream in vivo. In the present study, we assessed the effect of systemic administration of DEP on cardiovascular and respiratory parameters.