Publications by authors named "Israel Sunmola Afolabi"

Introduction: The growing incidence and high mortality rate of breast cancer (BC) in Nigeria is attributed to increased risk levels, poor prognosis and late detection.

Methods: This study aimed at identifying education-based disparities in BC risk knowledge, lifestyle/ dietary patterns among females in Ogun state, Nigeria. Questionnaires were used to obtain data from 1135 study participants across various levels of education and analyzed using Epi-info software and Graphpad prism.

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Purpose: Breast cancer (BC) is a major cause of cancer-related mortality in Nigeria, which is exacerbated by a lack of understanding of how knowledge of BC risk factors influences the lifestyle and dietary patterns of Nigerians across age groups. This study evaluated the influence of knowledge of BC risks on lifestyle and dietary patterns across age groups, aiming to inform early management, prevention, and survival rates.

Methods: A cross-sectional survey was conducted in Ota, Ado-odo, Ogun State, Nigeria, involving participants from six educational institutions.

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: Pharmacotherapeutic targets for breast cancer include the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (EGFR). Inhibitors of these receptors could be interesting therapeutic candidates for the treatment and management of breast cancer (BC). : This study used GC-MS and HPLC to identify bioactive compounds in () extracts and applied methods to identify potent EGFR, ER, and PR inhibitors from the compounds as potential drug candidates.

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Article Synopsis
  • * Mitochondria play a crucial role in ferroptosis by influencing energy production and generating reactive oxygen species, and changes in their structure and function are linked to this type of cell death.
  • * The review discusses how mitochondria impact ferroptosis mechanisms, particularly in malaria parasites, suggesting that targeting these organelles could enhance antiparasitic treatments by disrupting redox balance.
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Reactive oxygen species reacts with numerous molecules in the body system causing oxidative damage, which requires antioxidants to ameliorate. Pleurotus ostreatus, a highly nutritious edible mushroom, has been reported to be rich in bioactive compounds. This study evaluated the comparative antioxidant activity and phytochemical contents of five extracts of P.

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There is a huge gap between food production and the exploding population demands in various parts of the world, especially developing countries. This increases the chances of malnutrition, leading to increased disease incidence and the need for functional foods to reduce mortality. are edible mushrooms that are cheaply sourced and rich in nutrient with the potential to be harnessed toward addressing the present and future food crisis while serving as functional foods for disease prevention and treatment.

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grains are rich in phytochemicals known to considerably impact human health. Several health-promoting products such as flour, staple food, and beverages have been produced from sorghum grains. This study investigated the protective and modulatory effects of a sorghum diet on the genes of some antioxidant and glycolytic enzymes in alloxan-induced diabetic rats.

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A new plant milk was discovered from the seed of . The physicochemical and nutritional properties of the new pro-milk extract were assessed, and their biochemical effects were compared with those of soy bean extracts. Eleven groups of three albino rats each were used to assess the health benefits of the pro-milk.

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Benzyl isothiocyanate (BITC) is toxic in high concentration. The capacity of Aspergillus niger, microwave and ultraviolet radiations to reduce the BITC levels in Carica papaya Linn seed oil were assessed in vitro. BITC at different concentrations were periodically exposed to microwave and ultraviolet radiations for 30 min and 10 h, respectively; and to identify Aspergillus niger for 4 days.

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Background: Sickle cell disease (SCD) is a genetic disease caused by an individual inheriting an allele for sickle cell hemoglobin from both parents and is associated with unusually large numbers of immature blood cells, containing many long, thin, crescent-shaped erythrocytes. It is a disease prevalent throughout many populations. The use of medicinal plants and nutrition in managing SCD is gaining increasing attention.

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