The effect of angiotensin (1-7) on survival of random pattern skin flaps with nicotine-induced ischemia in rats.

Objective: The purpose of this study was to reveal the effect of angiotensin (1-7) on survival of random pattern, nicotinized, ischemic flap model in rats.

Materials And Methods: We used female Sprague Dawley rats weighing between 250 and 300 g. The study was performed on 3 groups each of them was consisted of 30 rats (control [C], angiotensin (1-7) [A] and vehicle [V]).