Publications by authors named "Ismaila Bouda"
Prevalence of asymptomatic parasitaemia among household members of children under seasonal malaria chemoprevention coverage and comparison of the performance of standard rapid diagnostic tests versus ultrasensitive RDT for the detection of asymptomatic parasitaemia in Nanoro, Burkina Faso.
Sié A Elisée Kambou Kié Solange Millogo Paul Sondo Bérenger Kabore Amélé Fifi Chantal Kouevi Ismaila Bouda
Parasitol Res
November 2024
Article Synopsis
- Asymptomatic carriers of Plasmodium falciparum play a crucial role in malaria transmission, prompting a study to assess malaria infection levels among household members of children receiving seasonal malaria chemoprevention (SMC).
- The study, which involved 745 participants and used various diagnostic tests, found that 26.58% of participants carried asexual forms of the parasite, with the highest prevalence (35.76%) among children aged 5 to 15 years.
- The ultrasensitive rapid diagnostic test (usRDT) showed greater sensitivity for detecting malaria compared to the standard rapid diagnostic test (rRDT), suggesting that usRDT is more effective for community-based screening and treatment strategies.
Background: Seasonal malaria chemoprevention (SMC) is an effective malaria preventive intervention in sub-Sahara Africa. However, as with any other drug-based intervention, the large-scale deployment of this strategy could lead to Amodiaquine plus Sulfadoxine-Pyrimethamine (AQSP) drug pressure on the circulating parasites population with selection for specific alleles that could compromise the impact of the intervention in the near future. This study aimed to assess the distribution of the Pfmdr1 mutation involved in resistance to AQ before and after the annual campaign of SMC in the health district of Nanoro.
View Article and Find Full Text PDFEnhanced effect of seasonal malaria chemoprevention when coupled with nutrients supplementation for preventing malaria in children under 5 years old in Burkina Faso: a randomized open label trial.
Paul Sondo Bérenger Kaboré Toussaint Rouamba Eulalie Compaoré Yssimini Nadège Guillène Tibiri Ismaïla Bouda
Malar J
October 2023
Article Synopsis
- In rural Burkina Faso, a study was conducted to assess the impact of combining Seasonal Malaria Chemoprevention (SMC) with nutrient supplementation among undernourished children under five years old, due to high levels of both malaria and malnutrition in the area.
- The study involved 1059 children divided into three groups, each receiving different combinations of SMC and nutritional interventions, followed over a year to monitor malaria incidence and overall health through regular check-ups.
- Results showed that adding lipid-based nutrient supplements (PlumpyDoz) significantly reduced both uncomplicated malaria (by 23%) and severe malaria (by 52%) compared to the control group, also lowering general illness rates by 24%, while no effect was found on