Publications by authors named "Ismail Rozila"
Article Synopsis
- This study explores how human adipose-derived stem cells (ASC) can differentiate into bone-forming cells when co-cultured with human osteoblasts (HOB) on specific scaffolds made from polycaprolactone (PCL) and hydroxyapatite (HA).
- Using different ratios of ASC and HOB in the co-culture, researchers assessed their growth and bone formation abilities through various tests including cell morphology, proliferation rates, and gene expression.
- Results indicated that a 2:1 ratio of ASC to HOB on PCL-HA scaffolds led to the best outcomes in terms of bone-related activity and gene expression, suggesting that this approach could effectively support early bone development.
The osteogenic potential of human adipose-derived stem cells (HADSCs) co-cultured with human osteoblasts (HOBs) using selected HADSCs/HOBs ratios of 1:1, 2:1, and 1:2, respectively, is evaluated. The HADSCs/HOBs were seeded on electrospun three-dimensional poly[(R)-3-hydroxybutyric acid] (PHB) blended with bovine-derived hydroxyapatite (BHA). Monocultures of HADSCs and HOBs were used as control groups.
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