MraZ Regulates Multiple Genes within and Outside of the Operon during Hypoxia.

is the most ancient human tuberculosis pathogen and has been the leading cause of death from bacterial infectious diseases throughout human history. According to the World Health Organization Global Tuberculosis Report, in 2022, 7.5 million new tuberculosis cases were identified, marking the highest number of cases since the World Health Organization initiated its worldwide tuberculosis surveillance program in 1995.

Mycobacterium marinum MMAR_0267-regulated copper utilization facilitates bacterial escape from phagolysosome.

The host limits Mycobacterium tuberculosis (Mtb) by enriching copper in high concentrations. This research investigates how Mtb escapes copper stress. The membrane protein encoded by Mtb Rv0102, when its homolog in M.

The Gene and Regulatory Network Involved in Ethambutol Resistance in .

Ethambutol (EMB) is used in combination with isoniazid and rifampicin for the treatment of tuberculosis caused by . However, the incidence of EMB resistance is alarming. The EMB targets the cell wall arabinan biosynthesis.