The daily supplementation of vitamin D is mandatory for infants. However, there are still conflicting opinions about the exact daily dose. Thus, we aimed to evaluate a daily supplementation dose of 200 IU is sufficient and compared the supplementation doses of 200 and 400 IU per day.
View Article and Find Full Text PDFJ Clin Res Pediatr Endocrinol
December 2011
Objective: The effect of ghrelin on growth of the newborn has long been argued, but not fully clarified. In this study, we aimed to investigate the relationship between ghrelin levels and growth parameters in the first 3 months of life.
Methods: The study included 60 babies (27 girls and 33 boys) born at gestational ages between 38-42 weeks.
Objective: To investigate the association between the clinical severity of childhood asthma and serum leptin levels, to define whether the severity of asthma correlates with body mass index (BMI) or serum leptin levels and to examine the sensitivity of leptin levels in predicting asthma severity.
Methods: This study was conducted in 65 patients, aged 2 to 14 yrs with newly diagnosed asthma without any chronic co-morbidity. The subjects were distributed into three groups according to the severity of asthma.
Objective: To evaluate the usefulness of renal zinc clearance/glomerular filtration rate ratio (R(ClZn)/GFR) as an indicator of marginal zinc deficiency that is generally associated with iron deficiency in childhood.
Methods: Zinc status was evaluated in 36 iron-deficient children (22 boys and 14 girls) who ranged in age from 1 to 10 years using serum zinc concentration and U(Zn/Cr) and R(ClZn)/GFR ratios. The results were compared with the zinc status of 36 similar-aged healthy children (24 boys and 12 girls).
J Pediatr Endocrinol Metab
May 2010
Background: Apelin is a novel adipocytokine produced by white adipose tissue that binds the APJ receptor with high affinity. Insulin may have a role in regulation of apelin synthesis and secretion from the adipose tissue.
Objective: To investigate blood apelin concentrations in children with type 1 diabetes mellitus (T1DM) and display association of apelin with adiponectin, body mass index (BMI), lipids and insulin sensitivity.
Aim: The aim of this study was to assess the adiponectin and visfatin concentrations in small-for-gestational age (SGA), appropriate-for-gestational age (AGA), and large-for-gestational age (LGA) newborns and their mothers. Sixty parturients giving birth to 20 term AGA singleton infants, 20 term singleton SGA infants, and 20 term singleton LGA infants were included into the study.
Results: Mean visfatin levels were found significantly higher in the SGA (p < 0.
Unlabelled: Streptococcus pneumonia is an increasing problem worldwide and nasopharyngeal colonization plays an important role in pneumococcal infections. The aims of this study were to assess the nasopharyngeal colonization rate, investigate the risk factors for nasopharyngeal colonization with S. pneumonia, serogroup and penicillin susceptibility patterns of Streptococcus pneumoniae strains isolated from healthy children.
View Article and Find Full Text PDFCerebello-oculo-renal syndromes are rare, autosomal recessive syndromes with uncertain nosology. Cerebello-oculo-renal syndromes involve many congenital malformations and may be associated with other disorders. The authors present a case of cerebello-oculo-renal syndrome with situs inversus totalis from a consanguineous family.
View Article and Find Full Text PDFThe papular-purpuric gloves-and-socks syndrome (PPGSS) is a disease characterized by an itching erythema and edema of the hands and feet, oral mucosal lesions and fever. It may be caused by various agents. Parvovirus B19 has been implicated as the etiological factor in most cases.
View Article and Find Full Text PDFThe aim of this study is to determine the normal values of serum cholesterol, triglyceride, VLDL-C, LDL-C, and HDL-C to obtain the reference values for diagnostic tests in healthy children. The study group included 420 healthy children (209 male, 211 female) ranging from 0 to 15 years. The cases were divided in 4 groups of age: 0-12 month (Group I), 13 month-6 year (Group II), 7-11 year (Group III), and 12-15 year (Group IV).
View Article and Find Full Text PDFObjective: To evaluate the efficacy of interferon (IFN) alpha-2b and lamivudine therapy in children with chronic hepatitis B virus (HBV) infection.
Method: Ten children who developed chronic hepatitis B infection received IFN alpha-2b 10 million international units (IU)/m(2) body surface area, subcutaneously three times a week for six months. IFN + lamivudine therapy began to be used in the cases who were unresponsive to IFN treatment.