Publications by authors named "Ismail Ak"

Article Synopsis
  • Naja species bites are a leading cause of consultations for snake envenomation in Malaysia, often resulting in severe neuroparalytic and cardiotoxic effects.
  • A reported case highlighted a 14-year-old boy who experienced cardiotoxicity, evident through an abnormal ECG, following a bite from the equatorial spitting cobra, Naja sumatrana, before showing signs of paralysis.
  • Timely administration of antivenom led to the resolution of symptoms, emphasizing the importance of monitoring for cardiotoxicity in envenomation cases to ensure quick treatment.
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Article Synopsis
  • - Snakebite envenomation is a major but often overlooked public health issue in tropical and subtropical regions, with particular challenges in medical infrastructure and record-keeping, especially concerning the King Cobra in Malaysia.
  • - A study from 2015 to 2020 analyzed 32 cases of King Cobra bites, primarily occurring in Peninsular Malaysia, where most victims attempted to catch or interact with the snake, leading to significant symptoms like ptosis and requiring advanced medical interventions.
  • - Most patients received antivenom treatment, primarily the monospecific King Cobra antivenom, but the study noted one death due to severe complications, highlighting the need for better public awareness and timely treatment to improve outcomes.
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This work explores the thermoluminescence (TL) and photoluminescence (PL) properties of Ag/Y co-doped zinc oxide (ZnO) nanophosphor. The proposed dosimeter was prepared by the coprecipitation method and sintered at temperatures from 400°C to 1000°C in an air atmosphere. Raman spectroscopy was studied to investigate the structural features of this composition.

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The present work is aimed to assess the protective influence of zinc oxide resveratrol nanoparticles against oxidative stress-associated testicular dysfunction. The number of 50 male albino rats were randomly separated into five groups (n = 10): Group I, control: rats gavage distilled water orally; Group II, Levofloxacin: rats that administered Levofloxacin (LFX) softened in distilled water at a dosage of 40 mg/kg BW orally every other day; Group III, Zn-RSV: rats administered with Zn-RSV (zinc oxide resveratrol in distilled water at a dose 20 mg/kg BW orally every other day; Group IV, (LFX + Zn-RSV): rats that were administered with Levofloxacin along with Zn-RSV nPs; Group V, Levofloxacin + Zn: rats were administered with Levofloxacin and Zno at a dose of 20 mg/kg BW orally every other day as mentioned before. This study lasted for 2 months.

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Radiation therapy can result in injury to the lung parenchyma and central airways; the latter is less well documented in the literature. Here, we describe a 65-year-old Caucasian male, who developed focal endobronchial nodules and right main bronchial stenosis suggesting tumour recurrence, 32 months following curative intent concurrent chemoradiation therapy for Stage 3B squamous cell carcinoma of the lung. Computed tomography and positron emission tomography results are detailed.

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Derris trifoliata is mainly found in mangrove area in tropical regions and the plant extract is traditionally used for fishing by poisoning. This is the first case report of rotenone poisoning in a child from ingesting Derris trifoliata seed. The child developed altered consciousness, vomiting, hypotension, metabolic acidosis, and acute kidney injury.

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Radiation therapy can result in injury to the lung parenchyma and central airways; the latter is less well documented in the literature. Here, we describe a 65-year-old Caucasian male, who developed focal endobronchial nodules and right main bronchial stenosis suggesting tumour recurrence, 32 months following curative intent concurrent chemoradiation therapy for Stage 3B squamous cell carcinoma of the lung. Computed tomography and positron emission tomography results are detailed.

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Jellyfish envenomation is a common marine injury. We report a case of a 9-year-old boy who developed muscle weakness and rhabdomyolysis after a jellyfish sting. He was stung on the face, hands, and feet.

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Article Synopsis
  • - The study examines the distribution and incidence of pit viper bites in Malaysia from January 2017 to December 2020, highlighting that the presence of species varies with altitude and geographical location.
  • - A total of 523 confirmed pit viper bite cases were reported, primarily among young adult Malaysian males, with the majority occurring in non-occupational settings and affecting the upper limbs.
  • - The commonest species involved was Trimeresurus purpureomaculatus, and the most frequently used antivenom was Green Pit Viper Antivenom, with most patients needing only one dose; the findings emphasize the need for adequate antivenom supply in regional hospitals.
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The successful application of glass-based materials in a wide range of scientific fields depends on the associated physical, optical, thermal, and mechanical properties. This article investigate the structural, Physical, thermal, optical, and mechanical properties of DyO, YO co-activated telluro-borate glass developed using the melt-quenching method. The glassy quality and the elements component of the specimens were observed using XRD and EDX analyses.

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Neurogastroenterology and motility is a new but advanced subspecialty within gasteroenterology that cater to difficult, persistent and refractory gut-brain symptoms. Hospital USM has the country's first and new state-of-the art motility lab that was recently launched on the 25 May 2023, and is covered in nationwide media. Another first is the Brain-Gut Clinic, established on the 16 November 2022.

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Patients bitten by typically experience significant pain, substantial swelling, and potentially blister formation. The appropriate dosage and efficacy of FHAV for alleviating local tissue injury remain uncertain. Between 2017 and 2022, 29 snakebite patients were identified as being bitten by .

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Article Synopsis
  • Jellyfish stings are a common cause of marine envenomation, with several species found around Penang Island, Malaysia, including box jellyfish which can cause severe reactions.
  • A 32-year-old man was stung by an unidentified jellyfish, experiencing immediate intense pain, chest discomfort, and breathing issues, and was treated with vinegar, analgesics, steroids, and antihistamines.
  • After refusing hospitalization, he later presented with worsening symptoms at a distant hospital, where tests revealed heart abnormalities and elevated enzyme levels, leading to symptomatic management and recommendations for better health-seeking behavior.
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The Puff Adder (Bitis arietans) is a viper native to Africa and the Middle East. Envenomation by this species often requires the administration of appropriate antivenom in order to achieve a favorable outcome. A patient was bitten in both hands by a captive B.

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Pit vipers from the genus Tropidolaemus are identified as one of the common causes of snake bite from venomous species in Malaysia. All Tropidolaemus species bite cases referred to the Remote Envenomation Consultation Services (RECS) between 2015-2021 were included. A total of 4,718 snake-related injuries cases consulted to RECS with 310 (6.

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Aflatoxins (AFs) are the most detrimental mycotoxin, potentially hazardous to animals and humans. AFs in food threaten the health of consumers and cause liver cancer. Therefore, a safe, efficient, and friendly approach is attributed to the control of aflatoxicosis.

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Objectives: To evaluate the safety and efficacy of expired lyophilized snake antivenom of Thai origin during a medical emergency in 2020/2021 in Lao People's Democratic Republic.

Methods: Observational case series of patients with potentially life-threatening envenoming who consented to the administration of expired antivenom between August 2020 and May 2022.

Results: A total of 31 patients received the expired antivenom.

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Background: Despite domestic production of antivenoms in the Association of Southeast Asian Nations (ASEAN) countries, not all victims with snakebite envenomings indicated for antivenom received the appropriate or adequate effective dose of antivenom due to insufficient supply and inadequate access to antivenoms. We aimed to conduct a cost-effectiveness analysis to project the potential economic and clinical impact of improving access to antivenoms when all snakebite envenomings in ASEAN countries were hypothetically treated with geographically appropriate antivenoms.

Methodology: Using a decision analytic model with input parameters from published literature, local data, and expert opinion, we projected the impact of "full access" (100%) to antivenom, compared to "current access" in five most impacted ASEAN countries, including Indonesia (10%), Philippines (26%), Vietnam (37%), Lao PDR (4%), and Myanmar (64%), from a societal perspective with a lifetime time horizon.

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Background And Aim: Salinomycin sodium, a licensed coccidiostat in rabbits, is used for fattening at a dose of 20-25 mg/kg. Salinomycin toxicity may arise from many risk factors (e.g.

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Background: Understanding the burden of snakebite is crucial for developing evidence-informed strategies to pursue the goal set by the World Health Organization to halve morbidity and mortality of snakebite by 2030. However, there was no such information in the Association of Southeast Asian Nations (ASEAN) countries.

Methodology: A decision analytic model was developed to estimate annual burden of snakebite in seven countries, including Malaysia, Thailand, Indonesia, Philippines, Vietnam, Lao PDR, and Myanmar.

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Naja sumatrana and Naja kaouthia are medically important elapids species found in Southeast Asia. Snake bite envenoming caused by these species may lead to morbidity or mortality if not treated with the appropriate antivenom. In this study, the in vitro neurotoxic and myotoxic effects N.

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This work examined the thermoluminescence dosimetry characteristics of Ag-doped ZnO thin films. The hydrothermal method was employed to synthesize Ag-doped ZnO thin films with variant molarity of Ag (0, 0.5, 1.

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