Publications by authors named "Ismael Sospedra"
Article Synopsis
- Skates, a type of cartilaginous fish, have unique wing-like pectoral fins that aid their survival in bottom-dwelling environments, but the genetic basis for this trait is not fully understood.
- Researchers analyzed the genome of the little skate species to uncover ancient vertebrate features and identified specific genomic changes that impact regulatory mechanisms involved in fin development.
- The study highlights the importance of genome restructuring and gene regulation in shaping skate fin morphology, emphasizing the role of the planar cell polarity pathway and a specific fin enhancer connected to hoxa gene expression.
Growth control relies on extrinsic and intrinsic mechanisms that regulate and coordinate the size and pattern of organisms. This control is crucial for a homeostatic development and healthy physiology. The gene networks acting in this process are large and complex: factors involved in growth control are also important in diverse biological processes and these networks include multiple regulators that interact and respond to intra- and extra-cellular inputs that may ultimately converge in the control of the cell cycle.
View Article and Find Full Text PDF