Publications by authors named "Ismael A Valderrama-Marquez"
Multicenter study in Colombia: Impact of a multidimensional International Nosocomial Infection Control Consortium (INICC) approach on central line-associated bloodstream infection rates.
Carlos A Álvarez-Moreno Sandra L Valderrama-Beltrán Víctor D Rosenthal Beatriz E Mojica-Carreño Ismael A Valderrama-Márquez
Am J Infect Control
November 2016
Background: The objective of this study was to analyze the impact of a multidimensional infection control approach and the use of the International Nosocomial Infection Control Consortium (INICC) Surveillance Online System on central line-associated bloodstream infection (CLABSI) rates from June 2003-April 2010.
Methods: We conducted a prospective, before-after surveillance study of 2,564 patients hospitalized in 4 adult intensive care units (ICUs) and 424 patients in 2 pediatric ICUs of 4 hospitals in 2 cities of Colombia. During baseline, we performed outcome surveillance of CLABSI applying the Centers for Disease Control and Prevention's National Healthcare Safety Network definitions.
Article Synopsis
- - Six strains of multiresistant Klebsiella pneumoniae, which produce the NDM-1 enzyme, were found during an outbreak affecting neonatal patients in a Colombian hospital.
- - Molecular examination revealed that all strains contained the blaNDM-1, qnrA, and intI1 genes and shared a close genetic relationship.
- - These strains represent a new sequence type (ST1043) never documented before, marking the first identification of NDM-1-producing bacteria in South America.