Publications by authors named "Islem Sanaa"

Background: In Tunisia, the number of cardiac implantable electronic devices (CIEDs) is increasing, owing to the increase in patient life expectancy and expanding indications. Despite their life-saving potential and a significant reduction in population morbidity and mortality, their increased numbers have been associated with the development of multiple early and late complications related to vascular access, pockets, leads, or patient characteristics.

Objective: The study aims to identify the rate, type, and predictors of complications occurring within the first year after CIED implantation.

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  • * The study included 915 patients, primarily middle-aged, where about 22.4% were found to have valvular AF, and only half of the patients with low embolic risk were prescribed oral anticoagulants.
  • * Findings highlighted that the management strategies for AF in Tunisia were inadequate, with concerns over low anticoagulation quality, as evidenced by a 1.64% thromboembolism rate and a notable number of patients not receiving proper antithrom
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Cardiac resynchronization therapy (CRT) is an effective treatment of heart failure in selected patients. However, with conventional CRT, notable left ventricular (LV) reverse remodelling is achieved in only 60-70% of patients. This lack of effect of CRT might be due to incomplete resynchronization.

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  • The study aimed to assess how often traumatic tricuspid regurgitation (TTR) occurs after the removal of implanted heart leads, identifying risk factors and patient outcomes.
  • Of 208 patients with 237 lead removals, 9.1% developed TTR, with higher risks linked to using laser sheath tools and being female.
  • Long-term follow-up showed that severe TTR was associated with considerable complications, including new symptoms of heart failure in some patients and mortality for others, emphasizing the need for careful monitoring.
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  • Clinical trials show that right ventricular apical pacing can lead to negative health outcomes, like heart dysfunction and long-term risks.
  • The study highlights how different pacing sites (right, left, and biventricular) can have both harmful and beneficial effects on heart function.
  • An algorithm is suggested to help guide the choice of pacing methods based on factors like heart conduction, left ventricular health, and patient lifespan.
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Background: Doppler echocardiography is currently the main tool permitting the diagnosis and the characterization of the stages of diastolic dysfunction.

Aim: The purpose of this study is to precise the contribution of Doppler tissue imaging in the study of diastolic function and to identify the parameters having the most discriminating power of diastolic dysfunction in hemodialysis patients.

Methods: Conventional Doppler echocardiography study implies left ventricular diastolic function from: Doppler transmitral flow (E/A, isovolumic relaxation time (TRIV), deceleration of mitral E-wave time (TDE), duration of A wave), color M-mode flow propagation velocity (Vp); The study of pulmonary venous flow (S/D, Systolic fraction (FS) and duration of pulmonary venous A wave); The annulus Doppler Tissue Imaging (Ea/Aa, E and A waves durations, VTI of E and A); and finally combined indexes (ratio of peak E-wave velocity to Vp (E/Vp), difference in duration between pulmonary venous and mitral flow A wave (Ap-Am) and ratio of peak mitral and annulus E-wave velocities (E/Ea).

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