[The formation of an immune response in volunteers inoculated with a live recombinant influenza vaccine].

The capacity of a live influenza vaccine (LIV) to stimulate cytotoxic cells (ADCMC and NK) was studied in 49 volunteers and 56 patients with influenza. Experimental batches of LIV from influenza A and B viruses prepared by genetic recombination on the basis of cold-adapted attenuation donors were used. Type A and B LIV were shown to stimulate the cytotoxic cell-mediated and humoral immunity; the intensity of immune response, however, depended on the molecular genetic characteristics of the vaccine (genome structure, properties of the donor of attenuation), its biological activity and capacity of reproduction in tissues.

[Effect of Essentiale on the blood lipid indicators in progressive Duchenne muscular dystrophy].

The authors showed a positive effect of the drug essential on both the lipid metabolism and motor function of their patients. The effect was most pronounced at initial stages of the disease.

[Plasma alpha/beta lipoprotein coefficient in the diagnosis of progressive muscular dystrophy].

Ten patients with Erb-Roth's progressive muscular dystrophy and 10 ones with Charcot-Marie neural amyotrophy have been examined. The blood plasma lipoproteins have been studied by disk electrophoresis in polyacrylamide gel with Reanal reagents. The studies have revealed different patterns of dyslipidemia and demonstrated the significance of alpha/beta lipoprotein coefficient in the diagnosis of such conditions.

[Clinical role of lipid metabolism indices in the plasma and erythrocytes in progressive muscular dystrophies].

Patterns of lipid metabolism were studied in blood plasma and erythrocytes of patients with various forms of hereditary myopathies (Duchenn disease, Bekker-Kiner disease, Erba-Roth disease, Landuzy-Dejerin disease, Sharko-Mary neural amyotrophy). These diseases were characterized by a number of common patterns: deficiency of phospholipids, specific alterations in properties of lipoproteins and in content of cholesterol. In the Duchenn disease specific alterations typical for each step of the disease were shown.

[Membrane pathology in human myodystrophy].

The authors studied the lipid composition of erythrocytic membranes and levels of pentane (a lipid peroxidation product) in the expired air in patients with Duchenne's myodystrophy. The changes found are discussed in the light of a hypothesis of the generalized membranous defect.

[Blood lipid disorders in Becker-Kiner progressive muscular dystrophy].

The article is devoted to one of the rare forms of hereditary neuromuscular diseases--Becker-Kiner progressive muscular dystrophy. Blood lipids were determined in nine patients aged 16 to 45 years with Becker-Kiner progressive muscular dystrophy. Profound disorders of the blood lipid metabolism were established which were expressed in hyperbeta-lipoproteinemia, hypertriglyceridemia, and hypercholesterinemia.

[Plasma lipids of patients with Duchenne's muscular dystrophy at different stages of the disease].

Blood plasma lipids were studied in patients with Duchenne's myodystrophy. The authors examined 40 patients, aged 3-16 years suffering from different stages of Duchenne's muscular dystrophy. Lipids and fractional composition of plasma phospholipids were investigated by thin-layer chromatography on "Silufol" plates; lipoproteins were assessed by the method of high voltage disk electrophoresis in polyacrylamide gel.