Publications by authors named "Islam Seada"

Article Synopsis
  • The study examined thyroid cancer cases at a hospital in Najran, Saudi Arabia, involving 279 patients from 2014 to 2021, primarily affecting women with a mean age of 42.8 years.
  • Most patients (60.9%) underwent total thyroidectomy, with a significant number showing localized disease; papillary and follicular cancers were the most common types.
  • Independent factors influencing mortality included older age, diabetes, certain cancer subtypes, and metastatic disease, with particularly high risks associated with tumor size and pulmonary metastasis.
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Background:  Reducing the frequency of emergency department (ED) patient visits for treatment, particularly in urgent instances, is a global healthcare objective. Additionally, a more extended stay in the ED can harm a patient's prognosis during later hospitalization. This study aims to investigate the factors affecting the length of stay in the ED in a teaching hospital.

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Background The COVID-19 pandemic significantly impacted healthcare systems globally, with cancer patients representing a particularly vulnerable group. This study aims to evaluate the influence of COVID-19 on cancer, focusing on infection rates, types of care, therapy adjustments, and factors associated with COVID-19 infection. Materials and methods This single-center retrospective analysis included adult cancer patients who underwent anticancer therapy at King Khalid Hospital in Najran, Saudi Arabia, from December 20, 2020, to January 23, 2022.

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Background: Chemotherapy-related cardiotoxicity can exhibit several patterns of functional, structural, and vascular complications. This study aims to identify the patterns and the factors associated with cardiotoxicity in cancer patients.

Method: A retrospective cross-sectional analysis of 96 adult cancer patients undergoing anticancer therapy was investigated at King Khalid Hospital in Najran, Saudi Arabia, from May 2022 to April 2023.

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Background: Lung cancer is one of the top causes of cancer deaths globally, including in Saudi Arabia. Although several prognostic markers have been established, the clinical features and outcomes of lung cancer in Saudi Arabia are not well understood. This study aimed to describe the clinical and therapeutic characteristics of advanced lung cancer in Najran, Saudi Arabia.

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Background Early detection of breast cancer is crucial for effective treatment and minimizing mortality, requiring effective screening methods like self-examination, clinical examination, and mammography. However, not all women in Saudi Arabia comply with these examinations, and studies examining its practice and barriers of low uptake are scant. The aim of this study is to investigate factors influencing breast cancer screening behavior among women in Saudi Arabia.

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Article Synopsis
  • Hepatocellular carcinoma (HCC) is a prevalent and deadly liver cancer in Saudi Arabia, often diagnosed at advanced stages, leading to poor treatment outcomes.
  • A retrospective study analyzed 52 HCC patients treated at Najran Oncology Center between April 2018 and June 2022, focusing on clinical data to identify mortality predictors.
  • Key findings include a median survival of 22.5 months, with disease progression as the main cause of death, and factors influencing mortality such as high alpha-fetoprotein levels and the presence of abdominal ascites.
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Background: Anemia, a common complication of cancer and its treatments, significantly affects cancer patients' survival and quality of life. Nevertheless, there is limited research conducted in the southern region of Saudi Arabia regarding its effects. This study aims to assess the prevalence of anemia, as well as its associated factors, among cancer patients undergoing active chemotherapy treatment.

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Article Synopsis
  • Cardiotoxicity is a significant concern for cancer patients undergoing treatment, manifesting as issues like acute coronary syndrome and heart failure; however, its prevalence among Saudi patients remains poorly understood.
  • A study at King Khalid Hospital over two years found that 15.4% of the 78 patients experienced cardiotoxicity, with common risk factors including hypertension and diabetes, and most patients were treated for breast or gastrointestinal cancers.
  • Key findings indicated that dyslipidemia, previous heart disease, and impaired baseline ejection fraction increased the risk of cardiotoxicity, while the administration of statins and antiplatelet agents appeared to reduce that risk.
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Cardiac cancers are exceedingly rare, mainly appearing as secondary cancers in patients with numerous systemic metastases, and are often detected by autopsies. Right ventricle (RV) metastasis from metastatic colorectal cancer (mCRC) is rarely reported in the literature. We report a 24-year-old man's case of mCRC, who developed positional variation in pulse rate while receiving the second cycle of chemotherapy.

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