The impact of melatonin on postoperative delirium in geriatric patients after colorectal surgery: a randomized placebo-controlled trial.

Background: The current study was designed to evaluate the role of prophylactic melatonin administration in reducing delirium occurrence in elderly patients undergoing colorectal cancer surgeries.

Methods: One hundred patients of both genders undergoing elective colorectal cancer surgeries under general anesthesia were randomly allocated into two equal groups. A treatment group of patients (Melatonin group) received five mg of melatonin the night before surgery, twelve hours before the scheduled surgery time, and an additional five mg of melatonin two hours before surgery.

Pulsatile nanofluid flow with variable pressure gradient and heat transfer in wavy channel.

This research contributes to the comprehension of nanofluid behaviour through a wavy channel, emphasizing the significance of considering diverse influences in the modelling process. The study explores the collective influence of pressure gradient variation, magnetic field, porosity, channel waviness, nanoparticle concentration, and heat transfer on nano-blood flow in a two-dimensional wavy channel. In contrast to prior research assuming a constant pulsatile pressure gradient during channel waviness, this innovative study introduces a variable pressure gradient, significantly influencing several associated parameters.

Dexmedetomidine as a part of general anaesthesia for caesarean delivery in patients with pre-eclampsia: A randomised double-blinded trial.

Background: During general anaesthesia, endotracheal intubation of patients with pre-eclampsia causes stimulation of the sympathetic nervous system and catecholamine release, which may lead to maternal and neonatal complications.

Objective: To attenuate both the stress response and the haemodynamic response to tracheal intubation in patients with pre-eclampsia.

Design: A randomised, double-blind, controlled study.

Slip Effects on Peristaltic Transport of a Particle-Fluid Suspension in a Planar Channel.

Peristaltic pumping induced by a sinusoidal traveling wave in the walls of a two-dimensional channel filled with a viscous incompressible fluid mixed with rigid spherical particles is investigated theoretically taking the slip effect on the wall into account. A perturbation solution is obtained which satisfies the momentum equations for the case in which amplitude ratio (wave amplitude/channel half width) is small. The analysis has been carried out by duly accounting for the nonlinear convective acceleration terms and the slip condition for the fluid part on the wavy wall.