Public exposure from inhalation of radon and thoron around the tin mine and smelter areas in Bangka, Indonesia.

Radon (Rn) and thoron (Rn) were reported as the highest contributors to natural radiation received by humans. Furthermore, radon has been stated as the second-highest cause of lung cancer. The concentrations of U and Th (the parent nuclide of radon and thoron, respectively) in nature vary with geological conditions and can be enhanced by human activities.

The trials and triumphs of co-producing an evaluation plan: A principles-focused evaluation.

Background: Recovery Colleges are mental health-oriented education programs that are rooted in principles of peer support and co-production. Co-production, in this context, involves people with lived experience of mental health and addiction challenges and people with other forms of expertise (e.g.

Rhodium complex [RhLI]I: a novel anticancer agent inducing tumor inhibition and apoptosis.

Numerous chemotherapeutic agents are currently employed in cancer treatment, but many are associated with significant side effects. This study aims to identify a novel anticancer drug that minimizes or eliminates these adverse effects. The anticancer activity of the Rhodium (III) complex cis-[RhLI]I was evaluated through both in vivo and in vitro functional assays.

All Roads Lead to Rome: Pathways to Engineering Disease Resistance in Plants.

Unlike animals, plants are unable to move and lack specialized immune cells and circulating antibodies. As a result, they are always threatened by a large number of microbial pathogens and harmful pests that can significantly reduce crop yield worldwide. Therefore, the development of new strategies to control them is essential to mitigate the increasing risk of crops lost to plant diseases.

FabricSpotDefect: An annotated dataset for identifying spot defects in different fabric types.

The FabricSpotDefect dataset is, to the best of our knowledge, the first dataset specifically designed to accurately challenge computer vision in detecting fabric spots. There are a total of 1014 raw images and manually annotated 3288 different categories of spots. This dataset expands to 2300 augmented images after applying six categories of augmentation techniques like flipping, rotating, shearing, saturation adjustment, brightness adjustment, and noise addition.

Associations between pre-existing comorbidities and in-hospital cardiovascular events and mortality among COVID-19 patients in Bangladesh: a secondary analysis of a prospective cohort study.

Objective: To identify the associations of in-hospital cardiovascular events and mortality with pre-existing comorbidities and cardiovascular disease (CVD) risk factors among COVID-19 patients in Bangladesh without vaccine availability.

Design: A secondary analysis of a prospective multicountry study.

Setting: Three COVID-19-designated hospitals in Bangladesh.

Evolutionary analysis of Quinone Reductases 1 and 2 suggests that NQO2 evolved to function as a pseudoenzyme.

Quinone reductases 1 and 2 (NQO1 and NQO2) are paralogous FAD-linked enzymes found in all amniotes. NQO1 and NQO2 have similar structures, and both catalyze the reduction of quinones and other electrophiles; however, the two enzymes differ in their cosubstrate preference. While NQO1 can use both redox couples NADH and NADPH, NQO2 is almost inactive with these cosubstrates and instead must use dihydronicotinamide riboside (NRH) and small synthetic cosubstrates such as N-benzyl-dihydronicotinamide (BNAH) for efficient catalysis.

Polygenic score analyses on antidepressant response in late-life depression, results from the IRL-GRey study.

Late-life depression (LLD) is often accompanied by medical comorbidities such as psychiatric disorders and cardiovascular diseases, posing challenges to antidepressant treatment. Recent studies highlighted significant associations between treatment-resistant depression (TRD) and polygenic risk score (PRS) for attention deficit hyperactivity disorder (ADHD) in adults as well as a negative association between antidepressant symptom improvement with both schizophrenia and bipolar. Here, we sought to validate these findings with symptom remission in LLD.

Ameliorating effects of leaves on lead-induced hepatotoxicity.

Lead (Pb), a common toxicant is ubiquitously present in the environment. Chronic Pb exposure affects almost every organ system of human body including liver. is a medicinal plant and its leaves are known to have hepatoprotective, anti-inflammatory, and anti-hyperglycemic activities.

The Potential of Artificial Intelligence in Unveiling Healthcare's Future.

This article examines the transformative potential of artificial intelligence (AI) in shaping the future of healthcare. It highlights AI's capacity to revolutionize various medical fields, including diagnostics, personalized treatment, drug discovery, telemedicine, and patient care management. Key areas explored include AI's roles in cancer screening, reproductive health, cardiology, outpatient care, laboratory diagnosis, language translation, neuroscience, robotic surgery, radiology, personal healthcare, patient engagement, AI-assisted rehabilitation with exoskeleton robots, and administrative efficiency.

Nanosilica and salicylic acid synergistically regulate cadmium toxicity in rice.

Cadmium (Cd) toxicity negatively impacts plant health and productivity. Nanosilica (SiONPs) and salicylic acid (SA) enhance plant performance and alleviate heavy metals stress. Yet, their combined effects against Cd-toxicity in rice remained less-explored.

A tumor-naive ctDNA assay detects minimal residual disease in resected stage II or III colorectal cancer and predicts recurrence: subset analysis from the GALAXY study in CIRCULATE-Japan.

Purpose: Analysis of circulating tumor DNA (ctDNA) may enable early identification of patients likely to relapse, presenting an opportunity for early interventions and improved outcomes. Tumor-naïve plasma-only approaches for molecular residual disease (MRD) assessment accelerate turnaround time, enabling rapid treatment decisions and ongoing surveillance.

Experimental Design: Plasma samples were obtained from 80 study participants with stage II or III colorectal cancer (CRC) selected from CIRCULATE-Japan GALAXY.

Assessment of musical interventions and its effect on blood pressure among United States populations: a systematic review and meta-analysis.

Background: Hypertension (HTN) currently affects over 120 million Americans, in the United States (US). Thus, the implementation of evidence-based interventions (EBI) for blood pressure (BP) reduction is pivotal in minimizing this burden. We sought to evaluate evidence from published literature on the effectiveness of musical interventions for BP reduction within the US.

Integrated geophysical and geospatial techniques for surface and groundwater modeling.

An integrated approach using geophysical and geospatial techniques was employed to model the surface and subsurface water-bearing strata and assess aquifer vulnerability in the Sehnsa town, Kotli district, State of Azad Kashmir, Pakistan. The inadequate scientific studies in the hilly terrain with such complex geological conditions has led to the failure of the boreholes for groundwater extraction. For the evaluation of groundwater potential and subsurface lithology, 30 vertical electrical soundings (VES) stations utilizing the Schlumberger electrode configuration were completed, modeled and analyzed spatially.

Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: a cross sectional study.

Arsenic is associated with lung disease and experimental models suggest that arsenic-induced degradation of the chloride channel CFTR (cystic fibrosis transmembrane conductance regulator) is a mechanism of arsenic toxicity. We examined associations between arsenic exposure, sweat chloride concentration (measure of CFTR function), and pulmonary function among 285 adults in Bangladesh. Participants with sweat chloride ≥ 60 mmol/L had higher arsenic exposures than those with sweat chloride < 60 mmol/L (water: median 77.

Cross-national variation in the prevalence and correlates of current use of reusable menstrual materials: Analysis of 42 cross-sectional surveys in low-income, lower-middle-income, and upper-middle-income countries.

Objectives: This study investigates the prevalence of the use of reusable menstrual materials in LMICs, examines differences in prevalence between countries and areas, and identifies individual and country-level factors associated with their use.

Methods: Data from Multiple Indicator Cluster surveys conducted between 2017 and 2020 in LMICs were used. Prevalence estimates and 95% CIs were calculated for overall, rural, and urban areas.

Health hazardous index based trace metals and essential acids analysis of size-dependent market available Hilsa fish, Bangladesh: Experimental and chemometric approaches.

With priority given to various-sized samples of market-available Hilsa (Tenualosa ilisha), human health consequences of trace metals along with total essential acids, including the fatty acid (FA) and amino acid (AA) profile were measured and compared to different size groups (G I, G II, and G III) using chemometric approaches. Essential amino acids were lower than nonessential amino acids. The G III contained the highest (97.