Publications by authors named "Islah Williams"

Invited for this month's cover is the group of Jean-Paul Desaulniers at Ontario Tech University. The cover picture shows the successful conjugation of a Ga-corrole to an siRNA to enable live cell imaging. Read the full text of the article at 10.

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Discovering new modifications for oligonucleotide therapeutics is essential for expanding its application to new targets and diseases. In this project, we focus on conjugating metaled ligands to short interfering RNAs (siRNAs) to investigate robust and simple conjugation methods for adding new properties such as real-time imaging to the siRNA. Here we report the chemical synthesis of novel Ga-(III)-corroles for their direct conjugation to siRNAs.

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