Publications by authors named "Iskandrian A"
Background: Implantable cardioverter-defibrillators (ICDs) improve outcomes in patients with heart failure (HF) with left ventricular ejection fraction (LVEF) ≤35%. Less is known about whether outcomes varied between the 2 noninvasive imaging modalities used to estimate LVEF-2-dimensional echocardiography (2DE) and multigated acquisition radionuclide ventriculography (MUGA)-which use different principles (geometric vs count-based, respectively).
Objective: The purpose of this study was to examine whether the effect of ICD on mortality in patients with HF and LVEF ≤35% varied on the basis of LVEF measured by 2DE or MUGA.
We have shown that silent myocardial infarction (SMI) on 12-lead ECG is associated with increased cardiovascular disease (CVD) risk in patients awaiting renal transplantation (RT). In this study, we evaluated the prevalence of SMI in patients undergoing RT and their prognostic value after RT. MI was determined by automated analysis of ECG.
View Article and Find Full Text PDFBackground: SPECT myocardial perfusion imaging (MPI) provides an assessment of LV mechanical dyssynchrony (LVMD) which correlates with CVD outcomes in diverse populations including those awaiting renal transplant (RT). The current study examines the association of LVMD on pre-transplant MPI with long-term CVD mortality post RT.
Methods: We identified consecutive patients who underwent RT at the University of Alabama at Birmingham between 2008 and 2012 from our prospectively collected database.
Article Synopsis
- A study investigated the impact of baseline right ventricular ejection fraction (RVEF) on the effectiveness of bucindolol, a beta-blocker, in patients with heart failure with reduced ejection fraction (HFrEF).
- Out of 2,798 participants, those with RVEF of 35% or greater showed a significant reduction in all-cause mortality when treated with bucindolol, whereas those with RVEF less than 35% did not.
- The findings suggest that RVEF could help identify patients who may benefit more from beta-blocker therapy, highlighting the need for further research with approved beta-blockers in similar patient groups.
Background: As the coronavirus pandemic progresses, patients that have recovered from COVID-19-related hospitalization require resumption of care for other medical issues. Thus far, the literature has not detailed the experience of stress testing in this patient population.
Methods: We retrospectively reviewed patients that recovered from COVID-19-related hospitalizations and underwent SPECT MPI studies at the University of Alabama at Birmingham Medical Center.
The ECG findings during sudden collapse (syncope or sudden death) in severe aortic stenosis (AS) are not well defined. We conducted a comprehensive review of the literature for ECG data during sudden collapse in patients with AS and provided a case report of our own. There were 37 published cases of syncope or sudden death in patients with severe AS which were documented by ECG.
View Article and Find Full Text PDFPrevalence of abnormal SPECT myocardial perfusion imaging during the COVID-19 pandemic.
Eur J Nucl Med Mol Imaging
July 2021
Purpose: The aim of this study is to evaluate the rate of abnormal myocardial perfusion imaging (MPI) studies at a single medical center during the COVID-19 pandemic compared to prior to the pandemic.
Methods: We retrospectively studied stress single-photon emission computed tomography (SPECT)-MPI studies performed during the peak of COVID-19 restrictions at the University of Alabama Medical Center in comparison to the same time period in 2019.
Results: SPECT-MPI volume was reduced from 553 per month in 2019 to 105 per month in 2020.