Evaluation of the relationship between mast cell activation and postural orthostatic tachycardia syndrome in children and adolescents.

Objective: Postural orthostatic tachycardia syndrome (POTS) is one of the orthostatic intolerance syndromes that are common in young adolescents and impair quality of life. POTS is a multi-systemic disease. Many mechanisms have been defined in POTS etiology, such as autonomic denervation, hypovolemia, hyperadrenergic stimulation, low condition, and hypervigilance.

Prospective evaluation of tolerance to unheated milk-boiled egg after baked milk-egg tolerance under 2 years.

Background: The time to acquisition of tolerance to unheated milk and regular egg after achievement of tolerance to baked goods is not known.

Objective: To determine the time to acquisition of unheated-milk-regular-egg tolerance, after the tolerance of the baked forms, in children younger than 2 years.

Methods: An initial oral food challenge with baked milk (BM) and baked egg (BE) was performed on patients who were reactive to unheated milk-regular egg, respectively.

A Prospective Assessment of Clinical Characteristics and Responses to Dietary Elimination in Food Protein-Induced Allergic Proctocolitis.

Background: Some aspects of diagnostic elimination/challenge diets in food protein-induced allergic proctocolitis (FPIAP) are still poorly defined.

Objective: This study investigated the symptom spectrum, time required for resolution of each symptom, triggering foods, and risk factors for multiple food allergies (MFA) in FPIAP.

Methods: Infants referred with visible blood in stool were enrolled after etiologies other than FPIAP had been excluded.

Food-induced anaphylaxis in early childhood and factors associated with its severity.

Several factors that increase the risk of severe food-induced anaphylaxis have been identified. We aimed to determine the demographic, etiologic, and clinical features of food-induced anaphylaxis in early childhood and also any other factors associated with severe anaphylaxis. We carried out a medical chart review of anaphylaxis cases from 16 pediatric allergy and immunology centers in Turkey.

Are large local reactions a marker for systemic reactions to subcutaneous immunotherapy in children?

Background: Previous studies involving predominantly adults concluded that the patients developing frequent large local reactions (LLRs) might be at greater risk for systemic reactions (SRs) during subcutaneous allergen immunotherapy (SCIT).

Objective: To determine the rate of side effects to SCIT and evaluate frequency of LLR among pediatric patients with SRs.

Methods: The retrospective study included pediatric patients receiving SCIT.

Mutational landscape of severe combined immunodeficiency patients from Turkey.

Severe combined immunodeficiency (SCID) has a diverse genetic aetiology, where a clinical phenotype, caused by single and/or multiple gene variants, can give rise to multiple presentations. The advent of next-generation sequencing (NGS) has recently enabled rapid identification of the molecular aetiology of SCID, which is crucial for prognosis and treatment strategies. We sought to identify the genetic aetiology of various phenotypes of SCIDs and assessed both clinical and immunologic characteristics associated with gene variants.

Determination of Dietary Status as a Risk Factor of Cardiovascular Heart Disease in Turkish Elderly People.

This study was performed to determine the status of diet as a risk factor of cardiovascular heart disease in a group of Turkish elderly people. We performed a cross-sectional study using the data of voluntary participants aged between 65-74 years old. Participants completed 3-day diet records.

The relationship between height and arm span, mid-upper arm and waist circumferences in children.

Background: Height is a significant parameter in assessment of growth, development, and nutritional status.

Objective: The aim of this study was to assess the relationship between height and arm span, mid-upper arm and waist circumferences in Turkish children.

Subjects And Methods: Height, arm span, mid-upper arm and waist circumferences were measured in 1145 boys and 1372 girls aged 7-14 years old from metropolitan Ankara schools in Turkey.

Body dysmorphic disorder in university students with skin diseases compared with healthy controls.

Body dysmorphic disorder appears relatively frequently in dermatological and cosmetic surgery settings; in fact, dermatologists may be the type of practitioner most often consulted by patients with body dysmorphic disorder. The aim of this study was to evaluate body dysmorphic disorder symptoms in Turkish university students with skin diseases. A total of 107 outpatients diagnosed with any skin disease and 109 age- and sex-matched healthy subjects recruited from the students of the same university were enrolled in the study.

Body image satisfaction and anxiety of a Turkish sample of university students with skin diseases.

The aim of this study was to evaluate perception of body image and anxiety of 221 university students presenting to the dermatology outpatient clinic with a skin disease and 205 students without skin disease. Analysis of anxiety and body image scores yielded differences by sex and age in both groups. The group with skin disease had lower scores on body image.