Publications by authors named "Isidora Stankovic"

Article Synopsis
  • Schizophrenia (SCZ) is a complex neurodevelopmental disorder that typically shows symptoms in early adulthood, and research is now focusing on how vascular dysfunction contributes to the disease.
  • Using patient-derived induced pluripotent stem cells (iPSCs), researchers created 3D cerebral organoids to study SCZ neuropathology, discovering that SCZ organoids had a higher percentage of endothelial cells compared to healthy controls (CTRL).
  • The study found significant changes in gene expression related to blood vessel formation and permeability in SCZ endothelial cells, suggesting that the brain's microvascular cells might influence the development of SCZ by impacting the blood-brain barrier's function.
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Background: Motor imagery is a cognitive process of imagining a performance of a motor task without employing the actual movement of muscles. It is often used in rehabilitation and utilized in assistive technologies to control a brain-computer interface (BCI). This paper provides a comparison of different time-frequency representations (TFR) and their Rényi and Shannon entropies for sensorimotor rhythm (SMR) based motor imagery control signals in electroencephalographic (EEG) data.

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The regulation of neurons by circadian clock genes is thought to contribute to the maintenance of neuronal functions that ultimately underlie animal behavior. However, the impact of specific circadian genes on cellular and molecular mechanisms controlling synaptic plasticity and cognitive function remains elusive. Here, we show that the expression of the circadian protein TIMELESS displays circadian rhythmicity in the mammalian hippocampus.

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Decades of research have unequivocally demonstrated that fetal exposure to both recreational and prescription drugs negatively impacts the developing brain. More recently, the application of cutting-edge techniques in neurodevelopmental research has attempted to identify how the fetal brain responds to specific environmental stimuli. Meanwhile, human fetal brain studies still encounter ethical considerations and technical limitations in tissue collection.

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One of the first environmental cues sensed by a microbe as it enters a human host is an upshift in temperature to 37°C. In this dynamic time point analysis, we demonstrate that this environmental transition rapidly signals a multitude of gene expression changes in Escherichia coli. Bacteria grown at 23°C under aerobic conditions were shifted to 37°C, and mRNA expression was measured at time points after the shift to 37°C ( = 0.

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