Publications by authors named "Ishandeep Singh"

Cannabis, one of the most widely used recreational drug in the United States, has had a significant surge in usage following its legalization in 1996. In recent years, there has been research into the physiological effects of cannabis on the gastrointestinal (GI) system. Our study aims to systematically examine the association between cannabis use and complications of gastroesophageal reflux disease (GERD).

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Background And Aims: Previous studies have reported gender differences in patients with gastroesophageal reflux disease (GERD). These studies have also reported differences based on gender in the rates of complications. In this study, we aim to identify gender disparities in the rates of GERD complications in the United States.

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Despite advancing treatment methods, esophageal cancer (EC) maintains a high mortality rate and poor prognosis. Through various mechanisms, aspirin has been suggested to have a chemopreventive effect on EC. However, the long-term impact, particularly regarding the rate of metastasis, needs to be further elucidated.

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Background: Clostridioides difficile infection (CDI) is a significant cause of morbidity and mortality among hospitalized patients, particularly those who are immunosuppressed. We aim to assess the outcomes of CDI among kidney transplant (KT) recipients.

Methods: Nationwide Inpatient Sample from 2016 to 2020 was used to identify patients with KT and stratify based on the presence of CDI.

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Objectives: Aspiration pneumonia is a rare but feared complication among patients undergoing esophagogastroduodenoscopy (EGD). Our study aims to assess the incidence as well as risk factors for aspiration pneumonia in patients undergoing EGD.

Methods: National Inpatient Sample 2016-2020 was used to identify adult patients undergoing EGD.

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Background: Inflammatory bowel disease (IBD) is an inflammatory disorder that can increase the risk of mortality. Aspirin is an anti-inflammatory drug used for primary prevention of cardiovascular events. A single center analysis previously reported that aspirin use did not impact major outcomes in IBD.

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Background: Liver transplant recipients (LTR) and patients with chronic liver disease (CLD) are at an increased risk of infections.

Aims: The objective of our study was to assess the incidence, and impact of vaccine preventable illness (VPI) on outcomes in LTR.

Methods: National Inpatient Sample (NIS) 2016-2020 was used to identify adults (age > 18) hospitalized LTR using ICD-10 codes.

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Introduction Gastroparesis (GP) is a chronic debilitating gastric motility disorder defined as delayed emptying of the stomach content without mechanical obstruction. It can result in nutritional deficiencies, leading to poor overall outcomes. We assessed the impact of malnutrition on in-hospital outcomes in patients with gastroparesis.

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Article Synopsis
  • More than half of people with inflammatory bowel disease (IBD) rely on the internet for information about their condition, with X (formerly Twitter) becoming a popular platform for healthcare-related discussions.
  • This study identified the top 100 influencers discussing IBD on X, primarily gastroenterologists and IBD advocates, with a majority based in the US, UK, and Canada.
  • A significant positive correlation was found between the influencers' engagement scores on X and their academic productivity, indicating social media can be a valuable resource for IBD information but also highlighting the need to combat misinformation online.
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Background/aims: Celiac disease (CD) is a T-cell-mediated gluten sensitivity that results in villous atrophy in the small intestine, leading to chronic malabsorption. Patients with celiac disease are prone to malnutrition. We assessed the impact of malnutrition on in-hospital outcomes in patients with CD.

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Introduction  Acute pancreatitis (AP) is a common inflammatory disorder with acute onset and rapid progression. Studies have reported cardiac injury in patients with AP. It is often thought that stress cardiomyopathy can induce these changes leading to type 2 myocardial infarction (type 2 MI) in AP.

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Background: Despite the use of new immunotherapies, hepatocellular carcinoma (HCC) has a poor survival rate. Through multiple molecular mechanisms, aspirin (ASA) has demonstrated a reduced incidence of HCC, however, the impact of long-term ASA use on in-hospital outcomes has not been studied.

Methods: We queried the National Inpatient Sample (NIS) database from 2016 to 2020 to identify patients with HCC.

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Article Synopsis
  • The study focuses on the impact of frailty in patients with liver disease undergoing transjugular intrahepatic portosystemic shunt (TIPS), revealing that frail patients experience worse post-procedural outcomes.
  • Using data from the National Inpatient Sample between 2016 and 2019, the researchers classified patients based on a Hospital Frailty Risk Score and found significant differences in mortality, hospital stay length, and overall costs between frail and non-frail patients.
  • The findings suggest that assessing frailty can enhance risk stratification and inform treatment decisions for patients undergoing TIPS procedures.
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