The effect of body weight on interfragmentary fracture strain in plate fixation of distal femur fractures: A finite element analysis.

Introduction: Distal femur fractures are difficult to successfully treat due to high rates of nonunion. Obesity is an independent prognostic risk factor for nonunion. Advances in finite element analyses (FEAs) have allowed researchers to better understand the performance and behavior of constructs at the bone-implant interface under a variety of conditions.

Direct Anterior Versus Posterior Approach for Total Hip Arthroplasty Performed for Displaced Femoral Neck Fractures.

Objectives: To compare perioperative, 90-day, and 1-year postoperative complications and outcomes between the direct anterior approach (DAA) and the posterior approach for total hip arthroplasty in geriatric patients with displaced femoral neck fractures (FNFs).

Design: Retrospective cohort study.

Setting: Multicenter Health care Consortium.

Impact of High-intensity Zones on Their Corresponding Lumbar Spine Segments: A Propensity Score-matched Analysis.

Study Design: Retrospective radiographic study.

Objective: The aim of this study was to compare disks with and without high-intensity zones (HIZ) to understand the impact of an HIZ on the stability of corresponding lumbar spinal segments.

Summary Of Background Data: Previous studies have established a relationship between back pain and the presence of HIZ on T2-weighted images of magnetic resonance imaging.

RDH1 suppresses adiposity by promoting brown adipose adaptation to fasting and re-feeding.

RDH1 is one of the several enzymes that catalyze the first of the two reactions to convert retinol into all-trans-retinoic acid (atRA). Here, we show that Rdh1-null mice fed a low-fat diet gain more weight as adiposity (17% males, 13% females) than wild-type mice by 20 weeks old, despite neither consuming more calories nor decreasing activity. Glucose intolerance and insulin resistance develop following increased adiposity.