Publications by authors named "Isha R Dabke"
Mol Cancer Ther
April 2019
Article Synopsis
- β-Arrestins, specifically ARRB1 and ARRB2, play significant roles in bladder cancer by influencing tumor behavior and response to chemotherapy.
- The study found that ARRB2 is an important independent predictor of metastasis and chemotherapy outcomes, showing around 80% accuracy in predicting clinical results.
- Altering levels of ARRBs affects cancer stem cell characteristics, with increased ARRB2 levels leading to reduced tumor growth and enhanced sensitivity to Gemcitabine treatment.
