Anti-aging and antioxidant of four traditional malaysian plants using simplex centroid mixture design approach.

Aging is a naturally biological process with adverse effects. The continuous accumulation of reactive oxygen species (ROS) trigger cellular and tissue damage by activating several aging enzymes. The antioxidant properties of traditional medicinal plants used by Jakun aborigine's community are a promising approach to alleviate aging process and prevent Alzheimer.

Chemical, Nutrient and Physicochemical Properties of Brown Seaweed, C. Agardh (Phaeophyceae) Collected from Port Dickson, Peninsular Malaysia.

Recent increased interest in seaweed is motivated by attention generated in their bioactive components that have potential applications in the functional food and nutraceutical industries. In the present study, nutritional composition, metabolite profiles, phytochemical screening and physicochemical properties of freeze-dried brown seaweed, were evaluated. Results showed that the had protein content of 8.

Chemical Composition and Evaluation of the -Glucosidase Inhibitory and Cytotoxic Properties of Marine Algae , and .

Seaweed has tremendous potentials as an alternative source of high-quality food products that have attracted research in recent times, due to their abundance and diversity. In the present study, three selected seaweed species commonly found in the Malaysian Peninsular, , and were subjected to preliminary chemical screening and evaluated for -glucosidase inhibitory and cytotoxic activities against five cancer cell lines. Chemical composition of and methanolic extracts was evaluated by Gas Chromatography-Mass Spectrometry (GC-MS) analysis.

Phytochemical Composition and Biological Activities of Selected Wild Berries (Rubus moluccanus L., R. fraxinifolius Poir., and R. alpestris Blume).

Berries, from the genus Rubus, are among the vital components in a healthy diet. In this study, 80% methanol extracts from the three wild Rubus species (Rubus moluccanus L., Rubus fraxinifolius Poir.

Molecular Docking Analysis of Selected Clinacanthus nutans Constituents as Xanthine Oxidase, Nitric Oxide Synthase, Human Neutrophil Elastase, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9 and Squalene Synthase Inhibitors.

Background: Clinacanthus nutans (Burm. f.) Lindau has gained popularity among Malaysians as a traditional plant for anti-inflammatory activity.

Phytochemical Constituents, Antioxidant and Antiproliferative Properties of a Liverwort, Lepidozia borneensis Stephani from Mount Kinabalu, Sabah, Malaysia.

The study aimed to investigate the phytochemical contents, antioxidant and antiproliferative activity of 80% methanol extract of Lepidozia borneensis. The total phenolic and total flavonoid contents were analysed using Folin-Ciocalteu and aluminium chloride colorimetric methods. Antioxidant properties were evaluated by using FRAP, ABTS, and DPPH assays while the effects of L.

Garcinia dulcis Fruit Extract Induced Cytotoxicity and Apoptosis in HepG2 Liver Cancer Cell Line.

Garcinia dulcis or locally known in Malaysia as "mundu" belongs to the family of Clusiaceae. The study was conducted to investigate the anticancer potential of different parts of G. dulcis fruit extracts and their possible mechanism of action in HepG2 liver cancer cell line.

Infrared-metabolomics approach in detecting changes in Andrographis paniculata metabolites due to different harvesting ages and times.

Background: The metabolite changes in three germplasm accessions of Malaysia Andrographis paniculata (Burm. F.) Nees, viz.

3,5-Dichloro-salicylaldehyde.

3,5-dichloro-2-hydroxy-benzaldehyde), C(7)H(4)Cl(2)O(2), crystallizes as discrete mol-ecules, the conformation of which may be influenced by an intra-molecular hydr-oxy-carbonyl O-H⋯O hydrogen bond.

4-Hydr-oxy-3-nitro-benzaldehyde.

The hydroxyl group in each of the two independent mol-ecules of the title compound, C(7)H(5)NO(4), participates in two O-H⋯O hydrogen bonds, viz. one intra-molecular bond to the nitro group and one inter-molecular bond to the aldehyde group of the same mol-ecule in the next unit, resulting in a linear chain structure. The dihedral angle between the aromatic ring and the nitro group is 10.

Low-temperature redetermination of 3,4,5,6-tetra-hydro-pyrimidin-2(1H)-one.

The low-temperature structure of the title compound, C(4)H(8)N(2)O, is ordered, whereas the central methyl-ene groups is disordered in the reported room-temperature structure. The molecule lies across a mirror plane; adjacent mol-ecules are linked by an N-H⋯O hydrogen bond into a chain.

3-Chloro-quinuclidinium chloride.

The cation of the title compound, C(7)H(13)ClN(+)·Cl(-), forms a linear hydrogen bond to the chloride anion. The cation is disordered about a mirror plane.

Optical fibre chemical sensor for trace vanadium(V) determination based on newly synthesized palm based fatty hydroxamic acid immobilized in polyvinyl chloride membrane.

Fatty hydroxamic acid (FHA) immobilized in polyvinyl chloride (PVC) has been studied as a sensor element of an optical fibre chemical sensor for V(V). By using this instrument, V(V) in solution has been determined in the log concentration range of 0-2.5 (i.