Publications by authors named "Isela Quintero"
Entamoeba histolytica causes amoebic liver abscess (ALA) in humans. The injury of target cells by E. histolytica includes processes controlled by the ubiquitin Ehub.
View Article and Find Full Text PDFThe ubiquitin-proteasome system plays a central role performing several functions to maintain parasite homeostasis. We have reported the partial characterization of N-linked glycosylation profile in E. histolytica ubiquitin (EhUb).
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- This study focuses on the N-linked glycosylation of ubiquitin in the parasite Entamoeba histolytica, revealing new insights into its ubiquitin-proteasome system.* -
- Various advanced techniques like FACE, NSI-MS, MALDI-TOF MS, and GC-MS were used to analyze the glycosylation profile, which was found to consist primarily of high mannose N-glycan structures.* -
- The findings suggest that ubiquitin may have different glycosylation patterns based on functional requirements, and the identified N-glycan structures could be potential targets for developing anti-amoebic drugs.*
Background/aims: Many parasites induce changes in the lipid profiles of the host. Cholesterol increases the virulence of Entamoeba histolytica in animal models and in vitro culture. This study aimed to determine, in patients with an amebic liver abscess, the correlation between cholesterol and other features, such as the size and number of abscesses, standard hematological and serum chemistry profiles, liver tests, and duration of hospital stay.
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