Publications by authors named "Iseki Y"

In this article, we investigate the encapsulation of K[Ni(maleonitriledithiolate)] () within a host molecule, β-cyclodextrin (β-CD), via single-crystal X-ray analysis. An inclusion complex, K{[Ni(maleonitriledithiolate)]@(β-CD)} (), was constructed from and two β-CDs. The anion guest Ni complex included a host cavity, constructed using two β-CDs, and the Ni atom of the anion was located between the two hydrophilic primary rims.

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  • The study aimed to determine how the CALLY index impacts patients with gastric cancer who have undergone gastrectomy, using data from 617 patients treated between 2014 and 2020 at Osaka City General Hospital.
  • Researchers calculated the CALLY index using a specific formula and compared it to other biomarkers to assess its predictive value for patient outcomes.
  • Results indicated that the CALLY index had the highest predictive value for overall survival and cancer-specific survival rates, making it a significant indicator for major complications in these patients.
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  • - The study investigated the relationship between the high frequency variability index (HFVI)/analgesia nociception index (ANI) and postoperative pain in patients undergoing video/robotic-assisted thoracoscopic surgery with nerve blocks under general anesthesia.
  • - Researchers looked at various measurements of HFVI/ANI and whether they could predict maximum postoperative pain levels and morphine usage, analyzing data from 48 patients.
  • - The findings indicated no significant correlation between HFVI/ANI and postoperative pain ratings or morphine consumption, suggesting that predicting postoperative pain in these cases using HFVI/ANI is challenging.
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  • The study investigated how the size of circular staplers affects complications like leakage and stricture during double-stapling technique anastomosis in colon or rectal cancer surgeries.
  • A total of 403 patients participated, using either small (25 mm) or medium-sized (28/29 mm) circular staplers.
  • Results showed no significant difference in complications between the two groups, indicating stapler size doesn't impact leakage or stricture rates.
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Esophageal duplication cysts are rare congenital noncancerous growths. Symptoms of this disease are reported to be asymptomatic in approximately 70% but include respiratory symptoms such as coughing and difficulty breathing. Minimally invasive removal of these cysts without esophagectomy is typically recommended.

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Background: Intra-abdominal infectious complications (IAICs) following minimally invasive gastrectomy (MIG) for cancer sometimes worsen short- and long-term outcomes. In this study, we focused on the minimum umbilicus-vertebra diameter (MUVD) in preoperative computed tomography (CT) images and robotic surgery to prevent severe IAIC occurrence.

Patients And Methods: A total of 400 patients with gastric cancer who underwent 204 laparoscopic gastrectomy (LG) and 196 robotic gastrectomy (RG) procedures were enrolled in this study.

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  • A study compared short-term and long-term outcomes for patients with early gastric cancer who underwent either esophagogastrostomy (EG) or double-tract reconstruction (DTR) after proximal gastrectomy (PG).
  • The research involved reviewing medical records of 34 patients who had EG and 39 who had DTR, looking at complications and nutritional status.
  • The findings indicated that while DTR took longer to perform, it had fewer issues like anastomotic stenosis and reflux, and both procedures showed similar long-term outcomes in terms of weight and overall survival.
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Background: Although frail patients are known to experience increased postoperative complications, this is unclear for postoperative pneumonia (POP). We investigated associations between frailty and POP in patients with gastric cancer (GC) undergoing gastrectomy.

Methods: In this prospective study conducted between August 2016 and December 2022, we preoperatively assessed frailty in 341 patients with GC undergoing gastrectomy using a frailty index (FI).

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Background: The efficacy of robotic gastrectomy (RG) on postoperative complications in patients with gastric cancer (GC) is unclear in terms of the volume of intra-abdominal fat tissue.

Patients And Methods: We enrolled 403 patients with GC who had minimally invasive surgery between January 2015 and July 2022. During this time, 197 RG and 206 laparoscopic gastrectomies (LG) were performed on the study participants.

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Complete mesocolic excision (CME) with central vascular ligation (CVL) in laparoscopic surgery for right-sided colon cancer (RSCC) requires a precise understanding of the vascular anatomy. The efficacy of intraoperative ultrasound (IUS) in the identification of blood vessels for RSCC surgery was not evaluated. The aim of this study was to compare the intraoperative and short-term outcomes of CME with CVL with or without IUS by laparoscopic surgery for RSCC.

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Introduction: Chest tube drainage is usually performed through an underwater seal at a level of 10-20 cmHO. Based on the definition of transpulmonary pressure, continuous chest drainage creates continuous negative pressure, decreasing pleural surface pressure and increasing transpulmonary pressure. We investigated how unilateral chest drainage could affect the tidal volume or driving pressure during mandatory mechanical ventilation.

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Introduction: Cancer cachexia occurs in cancer patients more frequently as the cancer progresses, with a negative impact on treatment outcomes. In this study, we sought to clarify the clinical impact of a cancer cachexia index (CXI) in patients with gastric cancer (GC) undergoing gastrectomy.

Methods: Between January 2013 and December 2018, we reviewed data from 556 patients treated for GC at our hospital.

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Background: The powered circular stapler, which was developed with the aim of providing reliable and reproducible anastomosis, provides complete anastomosis, resulting in a reduced risk of anastomotic leakage. The aim of this study was to compare the incidence of anastomotic leakage between a conventional manual circular stapler (MCS) and the ECHELON CIRCULAR™ Powered Stapler (ECPS) in patients with left-sided colorectal cancer who underwent anastomosis with the double stapling technique.

Methods: A total of 187 patients with left-sided colorectal cancer who underwent anastomosis with the double stapling technique with a conventional MCS or the ECPS during surgery at Osaka City University Hospital between January 2016 and July 2022 were enrolled in this study.

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Background/aim: In addition to oncological and treatment factors, the outcomes of cancer treatment are greatly influenced by host factors, such as the nutritional status. The aim of this study was to evaluate the association between the preoperative nutritional status and the prognosis of colorectal cancer patients using three nutritional indices.

Patients And Methods: The target cohort consisted of 529 patients with stage I-III colorectal cancer, who underwent curative surgery between January 2015 and December 2019.

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Background: To prevent anastomotic leakage in patients with left-sided colorectal cancer who underwent double-stapling technique (DST) anastomosis, we investigated a new method: DST anastomosis with a polyglycolic acid (PGA) sheet. This procedure has been shown to have the potential to decrease the rate of anastomotic leakage. However, due to the small number of cases enrolled in our previous study, it was not possible to compare the outcomes of the new and conventional procedures.

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Background/aim: Recently, the prognostic immune and nutritional index (PINI), which is calculated from the peripheral monocyte count and serum albumin level, has been reported to be useful as a prognostic marker in Korean and Chinese patients with colorectal cancer. The present study therefore examined the usefulness of the PINI as a marker for predicting the prognosis in Japanese colorectal cancer patients.

Patients And Methods: A total of 529 patients who underwent curative surgery for stage I-III colorectal cancer between January 2015 and December 2019 were enrolled in this study.

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Objective: The aim of this study was to clarify the risk of loss of independence (LOI) following gastrectomy in elderly patients with gastric cancer (GC).

Methods: In this prospective study, frailty was assessed preoperatively by a frailty index (FI) in 243 patients aged ≥ 65 years who underwent gastrectomy for GC between August 2016 and December 2020. Patients were assigned into two groups (high FI vs.

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Purpose: The Naples prognostic score (NPS) is a prognostic index based on the nutritional and inflammatory status. However, its utility in predicting postoperative complications (POCs) has not been examined in rectal cancer (RC). We evaluated the predictive value of the preoperative NPS for POCs in RC.

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  • An 86-year-old man was diagnosed with type 0-Ⅲ gastric cancer and underwent laparoscopic total gastrectomy, with the final diagnosis of stage ⅠB cancer showing no signs of recurrence for 5 years.
  • Eight years after the surgery, he experienced abdominal distention and anorexia, leading to the discovery of pleural fluid and ascites, but scans did not show any detectable recurrence.
  • Cytopathology revealed a late recurrence of gastric cancer affecting the pleura and peritoneum, but the patient declined treatment and passed away three months later, highlighting the rarity of such late recurrences.
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A 67-year-old man was introduced to examine for abnormal findings in physical examination. Upper gastrointestinal endoscopy detected the 3 lesions and diagnosed multiple gastric cancers with biopsy. Laparoscopic total gastrectomy was performed and final pathological diagnosis was pT2N1M0, pStage ⅡA with HER2 positive(3+).

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Background/aim: As D-dimer levels have been reported to reflect cancer activity, preoperative D-dimer levels may serve as a prognostic marker in patients with colorectal cancer. The aim of this study was to evaluate the prognostic significance of preoperative D-dimer levels in patients with stage I-III colorectal cancer who underwent curative surgery.

Patients And Methods: A total of 264 patients who underwent curative surgery for stage I-III colorectal cancer between January 2015 and December 2019 were enrolled in this study.

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  • - The study aimed to assess how biologic drugs influence the risk of advanced-stage intestinal cancer in patients with inflammatory bowel disease (IBD) using a comprehensive nationwide dataset.
  • - Analyzing records from 1,042 patients with Crohn's disease (CD) and ulcerative colitis (UC), it was found that biologics significantly reduced the risk of advanced-stage cancer in UC patients, but not in CD patients.
  • - The findings suggest different cancer progression mechanisms between UC and CD, highlighting the need for further research in understanding these differences.
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Background/aim: Predictive markers for survival and therapeutic efficacy in stage IV colorectal cancer have not been established. As described in our previous report, D-dimer levels may have potential utility as an indicator of cancer activity. The present study evaluated the significance of the D-dimer level as a marker for the survival and treatment outcomes in patients with stage IV colorectal cancer.

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