Mild, Fast, and Easy To Conduct MoCl-Mediated Dehydrogenative Coupling Reactions in Flow.

A convenient and straightforward approach to performing oxidative coupling reactions in flow is presented. A collection of electron-rich benzene derivatives was subjected to this protocol, and the distinct utility of molybdenum pentachloride (MoCl) is established. Using this unexplored protocol, biphenyls could be obtained in 21-91% isolated yield.