Evaluation of the efficacy and safety of gravitational therapy in a cohort of patients with systemic sclerosis.

Background: The exposure to artificial gravity (AG) through human centrifugation is the basis of the treatment called gravity therapy (GT), in which the mechanical stimulation over the vessel wall, induces the synthesis and release of prostacyclin. It has been used for more than four decades in Uruguay in the treatment of different vascular-based pathologies. In patients with systemic sclerosis (SSc) it has shown good benefits and excellent safety profile over the years.

The application of artificial gravity in medicine and space.

Gravity plays a crucial role in physiology. The lack of gravity, like in long duration spaceflight missions, cause pathologies in , the musculoskeletal system, cardiovascular deconditioning, immune system deprivation or brain abnormalities, to just mention a few. The application of artificial gravity through short-arm human centrifugation (SAHC) has been studied as a possible countermeasure to treat spaceflight deconditioning.

New transitional fossil from late Jurassic of Chile sheds light on the origin of modern crocodiles.

We describe the basal mesoeucrocodylian Burkesuchus mallingrandensis nov. gen. et sp.

Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain.

Background And Purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain.

Fossil evidence of the avian vocal organ from the Mesozoic.

From complex songs to simple honks, birds produce sounds using a unique vocal organ called the syrinx. Located close to the heart at the tracheobronchial junction, vocal folds or membranes attached to modified mineralized rings vibrate to produce sound. Syringeal components were not thought to commonly enter the fossil record, and the few reported fossilized parts of the syrinx are geologically young (from the Pleistocene and Holocene (approximately 2.

A Mesozoic bird from Gondwana preserving feathers.

The fossil record of birds in the Mesozoic of Gondwana is mostly based on isolated and often poorly preserved specimens, none of which has preserved details on feather anatomy. We provide the description of a fossil bird represented by a skeleton with feathers from the Early Cretaceous of Gondwana (NE Brazil). The specimen sheds light on the homology and 3D structure of the rachis-dominated feathers, previously known from two-dimensional slabs.

An enigmatic plant-eating theropod from the Late Jurassic period of Chile.

Theropod dinosaurs were the dominant predators in most Mesozoic era terrestrial ecosystems. Early theropod evolution is currently interpreted as the diversification of various carnivorous and cursorial taxa, whereas the acquisition of herbivorism, together with the secondary loss of cursorial adaptations, occurred much later among advanced coelurosaurian theropods. A new, bizarre herbivorous basal tetanuran from the Upper Jurassic of Chile challenges this conception.

Human centrifugation machine a physiological stimulator of endogenous prostaglandin synthesis.

A new model of human centrifugation machine with clinical purposes which makes possible to stimulate endogenous prostaglandin synthesis by a mechanical stimulus over the vessel walls is presented. The different therapeutical applications of this machine were demonstrated in lymphedema, peripheral obstructive arteriopathies, reflex sympathetic dystrophy syndrome, diabetic background retinopathy and coronary artery disease.

Human centrifugation: new approach in the treatment of diabetic background retinopathy (preliminary communication).

In previous studies we reported that Human Centrifugation Treatment (HCT) provoked endogenous prostaglandin liberation by a mechanical stimulus over the vessel walls. Up to now, the importance of Prostacyclin (PGI2) and HCT in the treatment of diabetic retinopathy has not been investigated. We studied the efficacy of one month of HCT in background retinopathy (BR).