Publications by authors named "Isar Sharma"

Gut dysbiosis and liver cirrhosis are two corelated complications that highly disturbs the metabolism of a normal human body. Liver cirrhosis is scarring of the hepatic tissue and gut dysbiosis is the imbalance in the microbiome of the gut. Gut dysbiosis in cirrhosis occurs due to increased permeability of the intestinal membrane which might induce immune responses and damage the normal functioning of the body.

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Background And Objectives: Cadherin13 () is an uncommon cadherin family member, lacking a transmembrane domain, and attaches via a glycosylphosphatidylinositol anchor to the peripheral surface of the cell membrane. plays an important role in the development and maintenance of axonal growth cones, synapse morphogenesis, and the embryonic neural tube. Cadherin superfamily genes have been associated with many neuropsychiatric diseases.

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Background: Neurogenic locus notch homolog 4 () regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The gene has also been identified as a possible susceptibility gene for schizophrenia (SCZ).

Aim: The study aimed to determine the association of polymorphisms with the risk of SCZ in the North Indian population of the Jammu region.

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