Long Term Outcomes of Liver Transplantation For Patients With Autoimmune Hepatitis.

Background: Autoimmune hepatitis (AIH) is a rare indication for liver transplantation (LT). Data on the long-term outcomes of living-related LT for AIH are limited and inconsistent. The present study aimed to assess the long-term outcomes of deceased donor LT (DDLT) and living donor LT (LDLT) for AIH.

Optimisation of T2 and T2* sequences in MRI for better quantification of iron on transfused dependent sickle cell patients.

This work aimed to investigate the effect of different shim techniques, voxel sizes, and repetition time (TR) on using theT2 and T2* sequences to determine their optimum settings to investigate the quantification of iron in transfused dependent sickle cell patients. The effect of each of these parameters was investigated on phantoms of different Gadolinium (Gd) concentrations, on 10 volunteers and 25 patients using a1 5T MRI Philips scanner. No significant difference between the three shim techniques was noticed in either T2 or T2* sequence measurements.

Lessons Learned from Large-Scale, First-Tier Clinical Exome Sequencing in a Highly Consanguineous Population.

We report the results of clinical exome sequencing (CES) on >2,200 previously unpublished Saudi families as a first-tier test. The predominance of autosomal-recessive causes allowed us to make several key observations. We highlight 155 genes that we propose to be recessive, disease-related candidates.

RADIOLOGICAL HAZARD INDICES OF GRANITIC ROCKS USED FOR THE CONSTRUCTION OF BUILDINGS FROM NUBA MOUNTAINS SUDAN.

This study was conducted to assess the level of radioactivity and the radiation hazards associated with granite rocks used for construction of buildings. The measurement of radioactivity content of the rock samples was performed with gamma-spectrometry equipped with Nal (TI) detector. From the results obtained in this study the average activity concentrations of 226Ra, 232Th and 40K were 20.

Effect of Downstaging and Bridging of Hepatocellular Carcinoma on Survival Following Liver Transplant: A Single Center Experience.

Objectives: Hepatocellular carcinoma is among the leading causes of cancer death. The Milan criteria are the first and most widely used criteria for selecting patients with hepatocellular carcinoma for a good transplant outcome. Studies have shown that patients with hepatocellular carcinoma outside the Milan criteria have good outcomes if they are successfully downstaged before transplant.

Environmental-Impact Assessment of Natural Radioactivity Around a Traditional Mining Area in Al-Ibedia, Sudan.

Recently, in the Sudan, traditional gold mining has been growing rapidly and has become a very attractive and popular economic activity. Mining activity is recognized as one of the sources of radioactivity contamination. Hence, the radioactivity concentration and radiological hazard due to exposure of radionuclides (226)Ra, (232)Th, and (40)K were evaluated.

Radiation survey of aircraft and heavy machinery scrap.

This study was conducted primarily to survey aircraft and heavy machinery at 30 locations within Khartoum State using handheld radiation survey meters to detect and identify any radiation sources that might be present and to estimate radiation dose levels. The survey has resulted in detection of 16 sealed sources of (90)Sr and one of (226)Ra in aircraft scrap. Of course, (90)Sr sources are used in military aircraft as temperature sensors while (226)Ra is used for indicating fuel levels.

Survey of computed tomography technique and radiation dose in Sudanese hospitals.

The purpose of this study was to survey technique and radiation absorbed dose in CT examinations of adult in Sudan and to compare the results with the reference dose levels. Questionnaire forms were completed in nine hospitals and a sample of 445 CT examinations in patients. Information on patient, procedure, scanner, and technique for common CT examinations were collected.

Progressive seizures in a patient with congenital coagulopathies.

Dural arteriovenous fistula (DAVF) is a rare complication of cerebral venous sinus thrombosis (CVST). DAVFs develop as a result of direct arterial to venous sinus communications evolving in response to an occluded sinus. The authors present a patient with Down's syndrome who developed progressive, uncontrolled seizures and chronic CVST secondary to factor V Leiden deficiency.

Investigation of natural radioactivity levels in water around Kadugli, Sudan.

Surface water from Miri Lake and groundwater from around Kadugli (West-Central Sudan) obtained by means of hand-pumps was analysed for (238)U, (226)Ra, (222)Rn, and (232)Th activity concentrations. The surface water showed very low levels of radionuclide concentrations: <1.0-7.

Quinine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan.

An observational clinical trial was conducted in New Halfa, eastern Sudan, in November and December 2003. Sixty-two patients with uncomplicated Plasmodium falciparum malaria were treated with oral quinine (10 mg/kg thrice daily for 7 d); 47 (76%) of these patients were followed-up to day 28, and 5 (10.6%) of them appeared to have late treatment failures.

Impact of fluoride and other aquatic parameters on radon concentration in natural waters.

Radon (222Rn) accumulation in water in relation to stable elements was studied for the purpose of determining factors influencing the transfer of 222Rn to and from water. In 72 groundwater samples, 222Rn and about 70 analytical parameters were analysed using radiometric and ICP-MS techniques. Using multivariate statistics (partial least squares), it was observed that 222Rn has a positive correlation with fluoride and uranium.

Uranium and thorium series radionuclides in drinking water from drilled bedrock wells: correlation to geology and bedrock radioactivity and dose estimation.

Natural radioactivity in drinking water from 328 drilled wells was studied in correlation to source parameters. Poor correlation to both aquifer geology and bedrock radioactivity was observed. Concentrations of 238U, 226Ra, 228Ra, 222Rn and 210Po in groundwater samples was in the ranges <0.