Publications by authors named "Isadora Alves Lustosa"

Article Synopsis
  • Aspirin, discovered in 1899 by Felix Hoffman, has been a top-selling drug for 125 years, serving as a major success in the pharmaceutical industry.
  • This review highlights various analytical methods used to study Acetylsalicylic Acid (ASA) and their relevance to current sustainable chemistry practices.
  • The predominant analytical techniques for ASA are HPLC and UV-Vis, mainly involving traditional solvents like methanol and acetonitrile, suggesting a need for greener solutions in the evaluation of this long-standing medication.
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Background: Clindamycin (CLIN), an antibiotic sold in the form of capsules, injectable solution, gel, and lotion, is easily soluble in water and ethanol. However, it lacks eco-efficient methods for evaluating pharmaceutical products.

Objective And Methods: The objective of this review is to provide an overview of the analytical methods present both in the literature and in official compendia for evaluating pharmaceutical matrices based on CLIN in the context of Green Analytical Chemistry (GAC).

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Background: Azithromycin (AZT) is an antimicrobial available in different pharmaceutical forms and many people can have access to this medicine. Therefore, the existence of adequate and reliable analytical methods for evaluating the quality of AZT and AZT-based products is essential.

Objective/methods: The purpose of this review is to discuss the analytical methods for evaluating AZT present in the literature and official compendia in the context of Green Analytical Chemistry (GAC).

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Moxifloxacin (MOX) is a fourth-generation fluoroquinolone used in the form of tablets, infusion solutions and ophthalmic solutions. It does not have a physical-chemical or microbiological analytical method described in an official compendium. However, the literature shows some analysis methods for pharmaceuticals and biological matrices.

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Background: Marbofloxacin (MAR) is an antimicrobial for veterinary use, and it does not have a monograph in an official compendium for the pharmaceutical form in tablets.

Objective: In this context, the objective of this work was to develop and validate an effective, eco-friendly, and indicative of stability method by spectrophotometry in the ultraviolet region (UV) for quantitative evaluation of MAR in tablets.

Method: Purified water-ethanol (80:20, v/v) as a diluent, quartz cubette and 296 nm were used.

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Background: Marbofloxacin (MAR), a second-generation fluoroquinolone, is used in veterinary medicine in the form of tablets. It has a broad spectrum of action, low toxicity, and limited development of bacterial resistance. The analytical methods available in the literature become more important since MAR in tablets does not have a monograph in official compendiums.

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