Publications by authors named "Isabelle Whittle"

Introduction: Adults aged ≥ 65 years contribute a large proportion of influenza-related hospitalizations and deaths due to increased risk of complications, which result in high medical costs and reduced health-related quality of life (HRQoL). Although seasonal influenza vaccines are recommended for older adults, the effectiveness of current vaccines is dependent on several factors including strain matching and recipient demographic factors. This systemic literature review aimed to explore the economic and humanistic burden of influenza in adults aged ≥ 65 years.

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Unlabelled: Post-COVID-19 conditions (PCC) is an umbrella term that encompasses a range of signs, symptoms and conditions present weeks after the acute phase of a SARS-CoV-2 infection. This systematic literature review summarises the heterogeneous methodology used to measure PCC across real-world studies and highlights trends by region, age group, PCC follow-up period and data source.

Methods: Medline, EMBASE and the Cochrane Library were searched and supplemented with conference and grey literature searches.

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Introduction: Adults aged 18-64 years comprise most of the working population, meaning that influenza infection can be disruptive, causing prolonged absence from the workplace, and reduced productivity and the ability to care for dependents. Influenza vaccine uptake is relatively low, even among the older adults in this population (i.e.

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Article Synopsis
  • Influenza is a serious respiratory infection that greatly affects adults aged 65 and older, who face higher risks due to age-related health issues.
  • A systematic review of studies from 2012 to 2022 showed significant clinical impacts globally, particularly in the USA and Europe, with increased hospitalization and mortality linked to specific flu strains like A(H3N2).
  • Despite higher vaccination rates in this age group, the current vaccines still provide limited protection, highlighting the urgent need for more effective vaccination strategies.
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