Publications by authors named "Isabelle Tron"
Long-term outcomes and predictors of disabling disease in a population-based cohort of patients with incident Crohn's disease diagnosed between 1994 and 1997.
Clin Res Hepatol Gastroenterol
November 2022
Background: The identification of early prognostic factors during Crohn's disease (CD) remains needed for physician decision-making to minimize structural bowel damage, which this study aimed to assess in a population-based setting.
Methods: All incident cases of CD were prospectively registered from 1994 to 1997 in Brittany, a limited area of France. All charts of patients were reviewed from the diagnosis to the last clinic visit in 2015.
Article Synopsis
- The study aimed to explore the incidence, outcomes, and predictors of perianal Crohn's disease (PCD) in a specific population in Brittany, France, by tracking patients from 1994 to 2015.
- Out of 272 patients with Crohn's disease, 18.7% had PCD at diagnosis, and over time, 34% developed PCD, with risks of conditions like anal ulceration and fistulizing PCD increasing over the years.
- The findings suggest that PCD is common in Crohn's disease and highlight the importance of targeted treatment strategies for early symptoms to prevent more severe complications like fistulizing disease.
Background: In France, although children aged less than 15 years with cancer are usually referred to pediatric oncology centers, adolescents may be treated at pediatric or adult oncology centers. The objective was to compare survival according to their site of treatment.
Procedure: Using population-based registration, 15- to 19-year-old patients diagnosed with cancer in 2006 or 2007 and living in six French regions (accounting for 41% of the French population) were included.
Background: In France, as in other countries, there is a need for a population-based view of access to care and modalities of treatment for adolescents with cancer.
Procedure: Using a population-based registration, we report pathways of care for 15-19-year-old patients, diagnosed with cancer in 2006 and 2007, living in six French regions, accounting for 41% of the French population.
Results: The median times (inter-quartile range) for diagnosis and treatment of the 594 included adolescents were 8 weeks (3-17) and 3 days (0-16), respectively.
The aim of this study was to describe the overall survival after childhood cancer in France using follow-up data from regional population-based registries. The survival of children (aged under 15 years) diagnosed with a cancer during 1990-1999 was analysed. For all cancers, the survivals were, respectively, 90.
View Article and Find Full Text PDFBackground: Cancer is the second most important cause of death for children aged less than 15 years in France, unintentional injuries being the leading cause. The aim of the present study was to estimate the incidence of childhood cancer from six Childhood Cancer Registries covering 32% of France.
Procedure: Incident cancer cases diagnosed between 1990 and 1999 in children (0-14 years) resident in the administrative areas covered by each Registry were included.
Crohn's disease in the over-60 age group: a population based study.
Eur J Gastroenterol Hepatol
July 2004
Objectives: Late-onset Crohn's disease (CD) may show a distinctive pattern of expression. The aim of our study was to describe the incidence or presentation of CD in the elderly and compare the outcomes in patients < 60 years or > or = 60 years at diagnosis.
Methods: The study included a population based inception cohort of all incident CD cases diagnosed in Brittany (France) between 1994 and 1997.