Predictors of Rapid Cognitive Decline in Patients with Mild-to-Moderate Alzheimer Disease: A Prospective Cohort Study with 12-Month Follow-Up Performed in Memory Clinics.

Background/aims: Alzheimer disease (AD) is particularly devastating, with no cure, no means of prevention, and no proven way to slow progression. AD is associated with the worsening of cognitive function attributable to a variety of factors of which little is known. Our main objective was to determine factors associated with rapid cognitive decline (RCD) in older AD patients.

Effectiveness of light paths coupled with personal emergency response systems in preventing functional decline among the elderly.

Introduction: The elderly population is at high risk of functional decline, which will induce significant costs due to long-term care. Dependency could be delayed by preventing one of its major determinants: falls. Light paths coupled with personal emergency response systems could prevent the functional decline through fall prevention.

Preventing and managing indoor falls with home-based technologies in mild and moderate Alzheimer's disease patients: pilot study in a community dwelling.

Background: Alzheimer's disease (AD) is known to increase the risk of falls. We aim to determine the effectiveness of home-based technologies coupled with teleassistance service (HBTec-TS) in older people with AD.

Methods: A study of falls and the HBTec-TS system (with a light path combined with a teleassistance service) was conducted in the community.

Efficacy of simple home-based technologies combined with a monitoring assistive center in decreasing falls in a frail elderly population (results of the Esoppe study).

Background: Increasing age often implies increasing frailty, and the oldest old are often described as a frail group with a high risk of developing functional impairments and multi-morbidities like falls at home, which often result in dependence in daily activities. This preliminary study evaluate the efficacy of light path coupled with tele-assistance service for preventing unintentional falls at home in a frail elderly population.

Methods: Study design is a longitudinal prospective cohort study from 1st July 2009 to 30 June 2010.

Background levels of metals in St. Lawrence River sediments: implications for sediment quality criteria and environmental management.

Preindustrial sediments dredged from the St. Lawrence Seaway are often considered potentially toxic relative to interim sediment quality criteria. The aim of the present study was to better document the background levels of target metals that were once used to define the minimal threshold of these criteria.

Exposure of caged mussels to metals in a primary-treated municipal wastewater plume.

The biological availability of metals in municipal wastewater effluents is strongly influenced by the physical and chemical conditions of both the effluent and the receiving water. Aquatic organisms are exposed to both dissolved and particulate (food ingestion) forms of these metals. In the present study, the distribution of metals in specific tissues was used to distinguish between exposure routes (i.

Distribution and fate of metals in the dispersion plume of a major municipal effluent.

The environmental impacts of municipal wastewater discharges on receiving waters are numerous and inputs of contaminants such as metals can cause toxicity to organisms in receiving waters. The effluents generated by the treatment plant of the city of Montreal, Canada, the largest such facility in the St. Lawrence Valley, was investigated to determine the environmental fate of trace metals in the receiving waters.