[Lung transplantation in cystic fibrosis].

Lung transplantation should be considered in cystic fibrosis patients with end-stage lung disease. The optimal time for pretransplantation evaluation rely on spirometric and gazometric criteria, as well as on the decline of pulmonary function and the degree of quality of life's impairment. Non-pulmonary complications of cystic fibrosis such as diabetes, osteoporosis and poor nutritional status should be evaluated, prevented and treated.

Successful management of severe respiratory failure combining heliox with noninvasive high-frequency percussive ventilation.

Heliox has been shown to be beneficial in the management of different obstructive pulmonary disorders. High-frequency percussive ventilation has recently been advocated to treat lung injury in children with reduced lung compliance. We report our experience of combining heliox with noninvasive high-frequency percussive ventilation in a 5-yr-old boy with severe acute respiratory failure resulting from advanced cystic fibrosis lung disease.