Serum from interferon-β-1b-treated patients with early multiple sclerosis stabilizes the blood-brain barrier in vitro.

Interferon-β (IFN-β) stabilizes the blood-brain barrier (BBB) in vitro. Here we investigated the effect of serum from 15 IFN-β-1b-treated multiple sclerosis (MS) patients on the permeability read-outs of small solutes in an in vitro BBB model consisting of human brain microvascular endothelial cells in co-culture with rat astrocytes. The addition of sera from IFN-β-treated patients resulted in a significantly (p < 0.

Arterial elongation ("redundancy") is not a feature of spontaneous cervical artery dissection.

The prevalence of elongation of the internal carotid arteries (ICA) is suggested to be significantly higher in patients with spontaneous cervical artery dissection (sCAD) than in other stroke patients. We reassessed this hypothesis in a case-control study by means of an improved semiautomated MR imaging technique. We compared the length of the cervical arteries in patients with and without sCAD.

High-resolution magnetic resonance imaging of triangular fibrocartilage complex lesions in acute wrist trauma: image quality at different field strengths.

Purpose: The purposes of this study were to assess the diagnostic capacity of a new high-resolution imaging protocol for the wrist and triangular fibrocartilage complex (TFCC) lesions at 3.0 T and to compare it with our established 1.5-T protocol.

High resolution 3.0 Tesla MR imaging findings in patients with bilateral Madelung's deformity.

Purpose: Madelung deformity (MD) is a rare, normally painful abnormality of the wrist and forearm which characteristically begins in adolescence. Usually the deformity appears between the age of 8 and 14 years, often progressing from initially mild functional pain to fatigue and loss of strength and finally, reduced mobility. We present the MR-findings in three patients with bilateral MD, using a high-resolution imaging protocol adapted for 3.

Neurosonographical follow-up in patients with spontaneous cervical artery dissection.

Objective: Neurovascular ultrasound (nUS) is widely used as a screening and monitoring tool in patients with spontaneous cervical artery dissection (sCAD). The aim of the study was to describe the sonographical course of the affected arteries in patients with a MRI-proven sCAD by repetitive nUS.

Methods: Thirty-seven consecutive patients aged<60 years with 1.

Detection of asymptomatic cerebral microbleeds: a comparative study at 1.5 and 3.0 T.

Rationale And Objectives: The magnitude of iron-induced susceptibility changes in gradient echo T2*-weighted magnet resonance imaging (T2* MRI) increases with the field strength and should increase the sensitivity for detection of cerebral microbleeds (CMBs) at 3.0 T. To test these hypotheses, we prospectively examined individuals with documented CMBs at 1.

High-resolution magnetic resonance imaging (MRI) at 3.0 Tesla in the short-term follow-up of patients with proven cervical artery dissection.

Purpose: For the imaging evaluation of patients with suspected cervical artery dissection (CAD) in the last decade, magnetic resonance imaging (MRI) has become the first line imaging modality. However, CAD is a highly dynamic process with rapid changes over time. Aim of this study was to assess the short-term morphologic changes in patients with proven CAD by MRI within 2 weeks after the initial diagnosis using a multicontrast high-resolution noninvasive vessel wall imaging approach at 3.

High-resolution magnetic resonance imaging of the temporomandibular joint: image quality at 1.5 and 3.0 Tesla in volunteers.

Purpose: To assess the image quality of a high-resolution imaging protocol for the temporomandibular joint (TMJ) at 3.0 T and to compare it with our standard 1.5 T protocol.

Spontaneous acute dissection of the internal carotid artery: high-resolution magnetic resonance imaging at 3.0 tesla with a dedicated surface coil.

Purpose: Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI.