Publications by authors named "Isabelle Mukagatare"
The ongoing outbreak of Marburg virus disease in Rwanda marks the third largest historically, although it has shown the lowest fatality rate. Genomic analysis of samples from 18 cases identified a lineage with limited internal diversity, closely related to a 2014 Ugandan case. Our findings suggest that the Rwandan lineage diverged decades ago from a common ancestor shared with diversity sampled from bats in Uganda.
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- The study explores the rising issue of bloodstream infections (BSIs) in Rwanda, focusing on the types of bacteria involved and their susceptibility to antibiotics from 2020 to 2022.
- A total of 1,532 blood culture tests were analyzed, revealing that Gram-negative and Gram-positive bacteria accounted for 48.2% and 51.8% of cases, respectively, with notable species being Staphylococcus aureus and Klebsiella.
- The findings highlight the effectiveness of various antibiotics, including Amikacin and Meropenem, in treating these infections, and suggest a need for improved strategies in managing antimicrobial resistance (AMR) in Rwanda.
Background: Existing data on the prevalence of hepatitis C virus (HCV) genotypes and subtypes in Rwanda need to be strengthened. The aim of this study was to identify HCV genotypes and subtypes among HCV-infected patients, as well as their geographical distribution in Rwanda, and to identify the social and economic factors that could influence HCV epidemiology which would make it possible to target national preventive and management actions for infected patients.
Methods: This study included 560 patients with confirmed chronic HCV infection.
Fungal infections (FIs) are spreading globally, raising a significant public health concern. However, its documentation remains sparse in Africa, particularly in Rwanda. This report provides a comprehensive review of FIs in Rwanda based on a systematic review of reports published between 1972 and 2022.
View Article and Find Full Text PDFThe East African Community (EAC) is experiencing an unprecedented, emerging mpox outbreak since July 2024 in five of eight partner states. We highlight rapid regional response measures, initiated August 2024 coordinated by EAC: field deployment of six mobile laboratories in Burundi, Rwanda, Uganda, Tanzania, Kenya, South Sudan to high-risk areas, donation of one mobile laboratory to Democratic Republic of the Congo and genomic monkeypox virus (MPXV) surveillance support. These interventions aim to limit local mpox spread and support international containment.
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