Background: The age of menarche has been gradually declining since the end of the 20th century. Few studies have been carried out about dysmenorrhea in Europe and they mainly included girls over the age of 15 years.
Methods: We conducted an observational study among sixth-grade schoolgirls (usually 11-12 years) during the 2020 academic year in 72 randomly selected public schools in a French region (approval number #20.
The synthesis of γ-lactams is reported by a formal (3+2) cycloaddition between readily available ketenes and aziridines or a one-pot formal (2+1+2) cycloaddition using imines as aziridine precursors. The method is practical, is scalable, and affords high yields. It also offers a high level of regio- and diastereoselectivity on a wide range of substrates as well as a high stereoselectivity in the case of enantiopure aziridines.
View Article and Find Full Text PDFJ Gerontol Soc Work
July 2018
The new political economy of aging portrays "active citizenship" among seniors as a key challenge for the years to come. As a policy framework, Active Aging ranks high on the agendas of most supranational bodies. Informed by discourse analysis and a narrative approach, this article focuses on, first, older women's everyday "active" practices, their meaning, and purpose and second, their day-to-day practical citizenship and social engagement experiences.
View Article and Find Full Text PDFThis article sets out to analyze how older women understand grandmotherhood. In-depth interviews were conducted with 25 elderly women from Quebec with diverse lives (widowed, married, single, with or without children) drawn from three generations (65-74 years, 75-84 years, 85 years and over) according to principles of qualitative analysis using grounded theory. Based on a constructivist approach, results highlight the evolution of images of grandmotherhood offering the benefit of emotional, playful and comforting roles.
View Article and Find Full Text PDFThe AdeABC pump of Acinetobacter baumannii BM4454, which confers resistance to various antibiotic classes including aminoglycosides, is composed of the AdeA, AdeB, and AdeC proteins; AdeB is a member of the RND superfamily. The adeA, adeB, and adeC genes are contiguous and adjacent to adeS and adeR, which are transcribed in the opposite direction and which specify proteins homologous to sensors and regulators of two-component systems, respectively (S. Magnet, P.
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