Exacerbated hemodynamic response during exercise in cancer patients prior to autologous hematopoietic stem cell transplantation.

Purpose: Chemotherapy treatment can lead to cardiovascular toxicity and physical impairment prior to autologous hematopoietic stem cell transplantation (auto-HSCT). Cardiovascular adjustments during exercise and the exercise capacity remain unknown in patients prior to auto-HSCT. Thus, the hemodynamic responses during exercise and exercise capacity were evaluated using a novel effort test in patients prior to auto-HSCT.

Autonomic and Vascular Control in Prehypertensive Subjects with a Family History of Arterial Hypertension.

Background: Individuals with a family history of systemic arterial hypertension (FHSAH) and / or prehypertension have a higher risk of developing this pathology.

Objective: To evaluate the autonomic and vascular functions of prehypertensive patients with FHSAH.

Methods: Twenty-five young volunteers with FHSAH, 14 normotensive and 11 prehypertensive subjects were submitted to vascular function evaluation by forearm vascular conductance(VC) during resting and reactive hyperemia (Hokanson®) and cardiac and peripheral autonomic modulation, quantified, respectively, by spectral analysis of heart rate (ECG) and systolic blood pressure (SBP) (FinometerPRO®).

Cardiac Autonomic Dysfunction in Offspring of Hypertensive Parents During Exercise.

Offspring of hypertensive parents present autonomic dysfunction at rest and during physiological maneuvers. However, the cardiac autonomic modulation during exercise remains unknown. This study tested whether the cardiac autonomic modulation would be reduced in offspring of hypertensive parents during exercise.

Baroreflex gain and vasomotor sympathetic modulation in resistant hypertension.

Purpose: The aim of this study was to determine the gain and latency of arterial baroreflex control of heart rate in patients with resistant hypertension compared to patients with essential hypertension and normotensive subjects.

Methods: Eighteen patients with resistant hypertension (56 ± 10 years, mean of four antihypertensive drugs), 17 patients with essential hypertension (56 ± 11 years, mean of two antihypertensive drugs), and 17 untreated normotensive controls (50 ± 15 years) were evaluated by spectral analysis of the spontaneous fluctuations of arterial pressure (beat-to-beat) and heart rate (ECG). This analysis estimated vasomotor and cardiac autonomic modulations, respectively.

Cardiac autonomic dysfunction in obese normotensive children and adolescents.

Objective: To test the hypothesis that obese normotensive children and adolescents present impaired cardiac autonomic control compared to non-obese normotensive ones.

Methods: For this cross-sectional study, 66 children and adolescents were divided into the following groups: Obese (n=31, 12±3 years old) and Non-Obese (n=35, 13±3 years old). Obesity was defined as body mass index greater than the 95th percentile for age and gender.

Cardiac autonomic modulation in healthy subjects with a family history of chronic kidney disease.

Introduction: The positive family history of chronic kidney disease (FH+) is a risk factor for the appearance and development of this disease. Thus, it is important to assess traits that may be related to familial predisposition to chronic kidney disease.

Objective: To evaluate the autonomic modulation by heart rate variability in individuals with FH+.