Objective: To assess the effectiveness and complication rate with Essure microinsert placements for tubal sterilization and the concomitant bipolar intrauterine surgical procedure.
Design: Case control study.
Setting: Department of gynecology and obstetrics of a general hospital in France.
Objective: To assess a new hysteroscopic method of tubal sterilization; specifically, to examine the factors associated with placement failure of Essure implants.
Design: Observational, multicenter, 6-month study.
Setting: Seven gynecology clinics, including five public hospitals and two private clinics, in France.
Reprod Biol Endocrinol
February 2003
Prolactin (PRL) exerts pleiotropic physiological effects in various cells and tissues, and is mainly considered as a regulator of reproduction and cell growth. Null mutation of the PRL receptor (R) gene leads to female sterility due to a complete failure of embryo implantation. Pre-implantatory egg development, implantation and decidualization in the mouse appear to be dependent on ovarian rather than uterine PRLR expression, since progesterone replacement permits the rescue of normal implantation and early pregnancy.
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