Publications by authors named "Isabelle Enderle"

Background: Preterm birth is a major health issue due to its potential outcomes and socioeconomic impact. Prenatal counseling is of major importance for parents because it is believed that the risk of preterm birth is associated with a higher parental mental burden. Nowadays in France, the content and delivery of antenatal counseling is based on personal experience since there is a lack of official guidelines.

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Objective: The aim of the study was a retrospective evaluation of labor induction in women with one previous cesarean section. The primary outcome was the mode of delivery. We also studied the severe maternal and neonatal morbidity and identify some prediction factors of vaginal delivery after labor induction after one previous cesarean section.

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Introduction: Despite awareness of obstetricians to the constant increase in the number of cesarean sections in recent years, the fear of a uterine scar rupture is still present and influences the choice of the mode of delivery in patients with two previous cesarean sections. However, several clinical studies have suggested that, under certain conditions, vaginal birth after two cesarean sections is usually successful and safe.

Objective: The objective of this study was to compare maternal and neonatal issues according to the planned mode of delivery in patients with two previous cesarean sections.

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Article Synopsis
  • About 15% of women in developed countries are exposed to solvents at work during pregnancy, but the effects on fetal growth vary based on the type of solvent (oxygenated, petroleum, chlorinated).
  • The study aims to explore how maternal exposure to different solvent families during pregnancy impacts the risk of neonatal outcomes, such as being small for gestational age (SGA) or having low birthweight.
  • Results indicate that exposure to petroleum and oxygenated solvents is linked to a higher risk of SGA and lower birth weights and head circumferences, highlighting potential risks of specific solvent types during pregnancy.
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Objective: The objective was to assess the predictive value of head-perineum distance measured at the initiation of the active second stage of labor on the mode of delivery.

Material And Methods: It was a prospective cohort study in an academic Hospital of Rennes, France, from July 1, 2020 to April 4, 2021 including 286 full-term parturients who gave birth to a newborn in cephalic presentation. A double-blind ultrasound measurement of the head-perineum distance was performed during the second phase of labor within five minutes after the onset of pushing efforts.

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Article Synopsis
  • Preeclampsia is a pregnancy-related condition linked to abnormal placentation, and there is growing suspicion that environmental chemicals like pesticides may contribute to this syndrome, although research has been limited.
  • This study examined the relationship between non-occupational pesticide exposure during pregnancy and preeclampsia risk in a cohort of 195 women with and 17,181 without the condition, using various data collection methods.
  • The findings indicated that higher levels of prochloraz near the homes of women with preeclampsia were associated with an increased risk, particularly for early diagnoses, while exposure to cypermethrin seemed to have a protective effect; no significant link was found between dietary pesticide exposure and preeclampsia
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Introduction: We aimed to assess the diagnostic yield of ultrasonography in the identification of the etiology of hydramnios, and the added value of MRI or amniocentesis.

Methods: We conducted a single-center retrospective study including pregnancies with confirmed hydramnios (defined as deepest pocket ≥8 cm) between January 2013 and May 2017. Twin pregnancies, secondary hydramnios discovered after the diagnosis of a causal pathology, and pregnancies of unknown outcome were excluded.

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Objective: To describe symptoms and fertility and quality of life outcomes after isthmocele surgery.

Study Design: We conducted a retrospective study on from January 2012 to December 2017 in two tertiary referral centers in Rennes (France). All the patients diagnosed with isthmocele and operated were included.

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Introduction And Hypothesis: The objective was to compare the outcomes of the ACT® device with those of the artificial urinary sphincter (AUS) AMS 800 in the treatment of stress urinary incontinence (SUI) due to sphincter deficiency in women.

Methods: All the women who underwent surgical treatment for SUI due to intrinsic sphincter deficiency from 2007 to 2017 were included in a single-center retrospective study. The primary endpoint was the functional outcome.

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Objective: To assess the diagnostic performance of the NG-Test human chorionic gonadotropin (hCG) WB, which is a new point-of-care (POC) hCG whole-blood test.

Materials And Methods: This prospective study included women consulted in early pregnancy units for vaginal bleeding and/or pelvic pain with unknown pregnancy status after medical consultation including a pelvic ultrasound scan. A new POC test (the NG-Test hCG WB) and the usual laboratory serum test (considered the gold standard) were performed in patients.

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