Publications by authors named "Isabelle Bernstein"

Background: Dairy cows are at high risk of fatty liver disease in early lactation, but current preventative measures are not always effective. Cows with fatty liver have lower circulating branched-chain amino acid (BCAA) concentrations whereas cows with high circulating BCAA levels have low liver triglyceride (TG). Our objective was to determine the impact of BCAA and their corresponding ketoacids (branched-chain ketoacids, BCKA) on production performance and liver TG accumulation in Holstein cows in the first 3 weeks postpartum.

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Article Synopsis
  • The study investigates the differences in metabolic profiles between high-efficient (HE) and low-efficient (LE) Holstein dairy cows to understand feed efficiency.
  • Using blood samples, researchers found that HE cows had lower levels of certain short-chain acylcarnitines and identified 39 differential metabolites related to energy and nutrient metabolism.
  • The analysis revealed differences in fatty acid and amino acid metabolism, suggesting that nutrient use efficiency may play a significant role in the variation of feed efficiency among individual dairy cows.
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