Publications by authors named "Isabelle Arctaedius"
Article Synopsis
- - The study aimed to assess the effectiveness of glial fibrillary acidic protein (GFAP) and total-tau in predicting neurological outcomes in patients who suffered cardiac arrest, comparing these biomarkers with neurofilament light (NFL) and neuron-specific enolase (NSE).
- - Conducted in three Swedish hospitals between 2014 and 2018, researchers examined blood samples from 428 cardiac arrest patients at various times post-arrest, finding that GFAP was a strong predictor of poor neurological outcomes at multiple time points.
- - Results indicated that while GFAP and tau show promise as biomarkers, NFL demonstrated equal or superior predictive capabilities compared to GFAP and tau after both out-of-hospital and in-hospital cardiac arrests. Additionally
Article Synopsis
- The study investigates the effectiveness of the 2021 ERC/ESICM neuroprognostication algorithm, expanding the entry criteria to include unconscious patients with Glasgow Coma Scale-Motor (GCS-M) scores of 4-5 and those under sedation.
- Conducted as a retrospective observational study across four ICUs in Sweden, it analyzed outcomes for postcardiac arrest patients treated between 2014 and 2018.
- Results showed that modifying the algorithm allowed for the identification of additional patients with poor outcomes, with a consistent false positive rate of 0% across various criteria assessments.
Article Synopsis
- This study investigates the effectiveness of neurofilament light (NfL) levels in predicting long-term outcomes in patients after out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) within the first 48 hours.* -
- Results showed that 68% of OHCA patients and 55% of IHCA patients experienced poor outcomes, with NfL exhibiting high prognostic accuracy at 12 and 48 hours post-OHCA (AUROC of 0.93 and 0.97), but lower accuracy for IHCA (AUROC of 0.81 and 0.86).* -
- The findings suggest NfL levels can reliably indicate outcomes as early
Introduction: Cardiac arrest is characterized depending on location as in-hospital cardiac arrest (IHCA) or out-of-hospital cardiac arrest (OHCA). Strategies for Post Cardiac Arrest Care were developed based on evidence from OHCA. The aim of this study was to compare characteristics and outcomes in patients admitted to intensive care after IHCA and OHCA.
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