Publications by authors named "Isabella Santos de Genaro"

Article Synopsis
  • Pulmonary irritants like cigarette smoke and sodium hypochlorite can worsen lung health in cleaning workers, leading to changes in lung mechanics and inflammation in Wistar rats.
  • Exposure to cigarette smoke alone caused increased airway inflammation and mucus production, while sodium hypochlorite elevated certain immune cell counts and inflammatory markers.
  • Interestingly, when both irritants were present together, they increased mucus acidity and altered lung structure, suggesting a potential adaptive response that might protect the lungs from further damage despite reduced overall inflammation.
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Aim: To explore the different consequences of acute and chronic exposure to chlorine gas (Cl) on the functional and histological parameters of health mice.

Main Methods: Firstly, male BALB/c mice were acute exposed to 3.3 or 33.

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Objectives: This study aimed to analyze the efficiency of physiotherapy techniques in sputum induction and in the evaluation of pulmonary inflammation in asthmatic children and adolescents. Although hypertonic saline (HS) is widely used for sputum induction (SI), specific techniques and maneuvers of physiotherapy (P) may facilitate the collection of mucus in some asthmatic children and adolescents.

Methods: A randomized crossover study was performed in patients with well-controlled asthma, and 90 sputum samples were collected.

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Work-exacerbated asthma (WEA) is defined as preexisting asthma that worsens with exposure to irritants [e.g., chlorine (Cl) derivatives] in the workplace.

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