Publications by authors named "Isabella Salgado"
Article Synopsis
- * Previous research showed that the anti-TNF-α drug Infliximab could stop seizures from ZIKV infection but didn't help with long-term cognitive or motor issues.
- * Prolonged treatment with Infliximab showed promising results in mice, preventing cognitive and motor deficits caused by ZIKV, suggesting that targeting inflammation could be a viable treatment strategy for those affected by the virus during development.
Galectins are a large and diverse protein family defined by the presence of a carbohydrate recognition domain (CRD) that binds β-galactosides. They play important roles in early development, tissue regeneration, immune homeostasis, pathogen recognition, and cancer. In many cases, studies that examine galectin biology and the effect of manipulating galectins are aided by, or require the ability to express and purify, specific members of the galectin family.
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