Effects of chronic restraint stress in the prostate of prepubertal and adult rats.

Purpose: To investigate the effects of chronic stress in the prostate of prepubertal and adult rats.

Methods: Thirty-two male rats were assigned into four groups depending on the type of treatment (control or stressed) and the age at which stress was initiated (prepubertal or adult). Restraint stress stimuli were applied for six weeks.

Histomorphometric comparison of the corpus cavernosum of rats submitted to euthanasia with ketamine and xylazine or isoflurane.

Purpose: To compare the penile histoarchitecture of rats euthanized with isoflurane or with ketamine and xylazine.

Methods: Fourteen male rats were divided into two groups: ISO, with animals euthanized with isoflurane; and K+X, with animals euthanized with ketamine (150 mg/kg) associated with xylazine (15 mg/kg). Immediately after the death, the penises were dissected, fixed in a 4% buffered formalin solution, and processed for histomorphometric analysis.