Publications by authors named "Isabella China Wang"
Acta Pharm Sin B
January 2024
Article Synopsis
- - The study explores using virus-like vesicles (VLV) to deliver three different immunomodulators (IL-12, shRNA targeting PD-L1, and dn-IL17RA) for enhanced cancer immunotherapy.
- - The combination payload, named CARG-2020, effectively eradicated large tumors and prevented their recurrence, leading to long-term survival in mice, indicating the benefits of using multiple immune mechanisms.
- - CARG-2020 not only activated powerful immune responses but also demonstrated protection against tumors that weren’t directly injected, suggesting it helps create lasting immunity and could be a strong candidate for cancer treatment in humans.
