Publications by authors named "Isabell Holzer"
J Assist Reprod Genet
November 2020
Article Synopsis
- Endometriosis (EM) affects 10-15% of women of reproductive age, but its molecular mechanisms are not fully understood, and diagnosis typically relies on laparoscopic surgery due to a lack of clinical biomarkers.
- Researchers analyzed endometrial tissue samples from 58 women to investigate gene and protein expression of specific molecules (GRN, NOTCH3, FN1, PINK1) associated with EM.
- Findings indicate that GRN and FN1 may serve as potential clinical biomarkers for detecting endometriosis, with variations in expression correlating to disease severity, but further research with a larger sample size is required to validate these results.
